New Drug Trial Aims To Prevent Alzheimer’s Before It Starts

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Researchers will test an experimental drug that could prevent Alzheimer’s disease in people who are genetically slated to develop Alzheimer’s disease but have yet to exhibit symptoms

As part of the National Alzheimer’s Plan, the National Institutes of Health (NIH) awarded a $16 million grant to Banner Alzheimer’s Institute in Arizona to fund the Alzheimer’s Prevention Initiative (API), which will study whether a plaque-fighting treatment can prevent the disease. The trial will take place in Medellín, Colombia as well as select sites in North America. The majority of the study participants will come from an extended family of 5,000 people living in Medellín who are considered part of the world’s largest family affected by Alzheimer’s. The New York Times reports the family members have a specific genetic mutation that causes symptoms of cognitive impairment around age 45, then full dementia around age 51.

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Alzheimer’s Disease: 7 Habits That Could Lower Your Risk

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USA Today pointed out that nearly 5 million people in the United States already have Alzheimer’s disease. That number could triple by 2025 as the U.S. population ages, the publication reported.

The upcoming research is exciting, but there are also some things we already know about the prevention of dementia and Alzheimer’s. Click through to see what science has shown — or at least suggested — to work at warding off the memory-robbing condition.

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Clock ticking with new plan to fight Alzheimer’s

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The clock is ticking: The first National Alzheimer’s Plan sets a deadline of 2025 to finally find effective ways to treat, or at least stall, the mind-destroying disease.

The Obama administration finalizes the landmark national strategy on Tuesday, laying out numerous steps the government and private partners can take over the coming years to fight what is poised to become a defining disease of the rapidly aging population.

But some of the work is beginning right away.

Starting Tuesday, embattled families and caregivers can check a new one-stop website — www.alzheimers.gov — for easy-to-understand information about dementia and where to get help in their own communities.

The National Institutes of Health is funding some major new studies of possible therapies, including a form of insulin that’s squirted into the nose.

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Omega-3s may help lower risk of Alzheimer’s disease

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Eating foods such as chicken, fish and nuts may help lower blood levels of a protein strongly associated with Alzheimer’s disease and memory problems, according to new research.

In the Columbia University study, people who consumed diets rich in omega-3 fatty acids had significantly lower levels of a protein called beta-amyloid in their blood than those who did not consume as much of the nutrient.

According to the research, eating one more gram of omega-3s than average per week was associated with 20 to 30 percent lower levels of beta-amyloid.  One gram is approximately equal to half a fillet of salmon.

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New Alzheimer’s Caregiver Website by MindStart Keeps Minds Active

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The http://www.mind-start.com website for people with Alzheimer’s and other dementias and their caregivers, is the only one of its kind, providing both products for dementia care and educational content and support. The focus of the website is to keep people with dementia active by offering tools and resources to caregivers, both family and professional.

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How to Protect Against Alzheimer’s Disease

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Charles Snelling spent six years taking care of his Alzheimer’s-stricken wife, Adrienne, helpless as he watched the disease steal his college sweetheart. In March, after six decades of marriage, Snelling killed his longtime partner, and then he killed himself. Both were 81. “After apparently reaching the point where he could no longer bear to see the love of his life deteriorate further, our father ended our mother’s life and then took his own life as well,” his children said in a statement. “This is a total shock to everyone in the family, but we know he acted out of deep devotion and profound love.”

Indeed, Alzheimer’s disease unleashes a devastating, sometimes unmanageable burden. It is a leading cause of disability and death, with numbers poised to explode in coming years as the older population grows. (Symptoms typically first appear after age 60.) By 2050, an estimated 16 million people will be diagnosed with Alzheimer’s, the most common type of dementia, and roughly 5.4 million Americans are currently living with the condition, according to a March report by the Alzheimer’s Association, a nonprofit advocacy group. One person develops Alzheimer’s every second. It’s the 6th leading cause of death in the United States, and the 5th for those age 65 and older. And there’s no cure. “We should be very worried,” says Reisa Sperling, director of the Center for Alzheimer’s Research and Treatment at Brigham and Women’s Hospital in Boston.

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