Dr. Salloway was part of a group that came out with new guidelines advising physicians to prescribe spinal taps for people who either have memory loss or have a family history, as a way to diagnose Alzheimer’s — getting them into prevention trials sooner rather than later.
Results from two studies show that a new, non-invasive imaging device can see signs of Alzheimer’s disease in a matter of seconds. The researchers show that the small blood vessels in the retina at the back of the eye are altered in patients with Alzheimer’s. Even patients who have a family history of Alzheimer’s but have no symptoms show these telltale signs.
Studies published in July 2018 suggest that some cases of Alzheimer’s and some other types of dementia might be triggered by infection of brain cells with viruses, primarily the herpesviruses (especially human herpesvirus 6A).
New trial’s results are now the first solid confirmation that lowering blood pressure reduces the risk of both mild cognitive impairment (MCI), a degree of brain decline that’s considered the gateway to dementia, and probable dementia.
According to entrepreneur and philanthropist Bill Gates, a key need is a “reliable, affordable, and accessible” diagnostic test. To jump-start that research, Gates announced today that he has joined a coalition of philanthropists who are investing $30 million to create a venture fund called Diagnostics Accelerator.
You can’t tell how healthy someone is just by looking at them, but that doesn’t mean people don’t make assumptions, especially when they’re factoring in weight. But what about people who are “skinny-fat”? According to a new study, this body type, which is characterized by a combination of high fat mass and low muscle mass, may actually be worse for your health than obesity alone.
With two of the last drug-makers abandoning their late stage trials, the familiar question comes up again: Why would you want to know if you have Alzheimer’s when there is no cure? The opinions are divided.
The early signs of Alzheimer’s centre around forgetfulness, which means that often loved ones – whether partners, family or friends – are best-placed to notice behavioral changes. Encouraging your partner to see his or her GP as early as possible is advisable.
Scientists have recently made a major discovery that could lead to a breakthrough in the treatment of Alzheimer’s disease. A recent study published in Nature Medicine reports that researchers were able to identify the primary genetic risk factor the development of the disease, and they even figured out a potential way to neutralize the risk factor.
Government and other scientists are proposing a new way to define Alzheimer’s disease — basing it on biological signs, such as brain changes, rather than memory loss and other symptoms of dementia that are used today.
Research from the University of Texas at San Antonio suggests that the plaques that cause the symptoms of Alzheimer’s disease may be more complicated than previously believed, a finding that could significantly affect drug development for the disease.
Researchers found that in addition to the sticky proteins called amyloid beta, other neural and repair proteins also exist within the plaques, indicating new biomarkers for the disease that affects more than 5 million people in the United States.
Most people associate dementia with short-term memory loss; someone with the condition can’t remember the prime minister’s name or where they left their car keys. But that inability to recall simple facts is not the only early sign of dementia, says Dr Selina Wray, Alzheimer’s Research UK senior research fellow and winner of the Alzheimer’s Research UK David Hague Early Career Investigator of the Year Award 2018.
Spotting the first indications of Alzheimer’s years before any obvious symptoms come on could help pinpoint people most likely to benefit from experimental drugs and allow family members to plan for eventual care. Devices equipped with such algorithms could be installed in people’s homes or in long-term care facilities to monitor those at risk. For patients who already have a diagnosis, such technology could help doctors make adjustments in their care.
The device works very similar to a pacemaker that is used in heart patients, except the wires go to a specific section of the brain. The wires stimulate “sickish” cells in the brain and help to restore functionality.