“I don’t want to raise false hopes,” Researcher Bloom said, but “if this idea of using memantine as a prophylactic pans out, it will be because we now understand that calcium is one of the agents that gets the disease started, and we may be able to stop or slow the process if done very early.”
Is it good to get our hopes up with every bit of good news, or is the disappointment when it turns out not to be the magic bullet too much?
A promising new drug called BAN2401 generated a lot of excitement after a clinical trial found it slowed the progression of Alzheimer’s by 30%, but recent revelations have left investors and doctors with more questions than answers, reports Bloomberg.
A new study indicates that patients with high blood pressure are at a higher risk of developing dementia. This research also shows (for the first time) that an MRI can be used to detect very early signatures of neurological damage in people with high blood pressure, before any symptoms of dementia occur.
Move For Minds is a partnership created four years ago with Equinox.They go into these gyms where people were concerned about their bodies, focused on fitness, and try to spread the message about brain fitness to them. The goal is to get people thinking not just about their bodies, but their brains, because what we now know about Alzheimer’s is that it’s 20 years or longer in your brain. And we’re trying to get the message about caring for your brain and preventing Alzheimer’s to people who are in their 30s and 40s.
UC San Diego and Scripps Research Institute scientists announced Wednesday they have identified a gene that prevents harmful protein deposits, or “aggregates,” associated with neurological disorders such as Alzheimer’s and Parkinson’s disease.
Numerous studies suggest being overweight during middle age increases the risk of developing Alzheimer’s. A new study by the National Institutes of Health found that people who are obese at age 50 may develop, or have a higher risk for, younger-onset Alzheimer’s disease.
“While spare change doesn’t seem like a lot, automatically rounding up one’s transaction adds up to about $50 per month on average,” Tokarsky said. “Just think about it. Does it really make sense for millions of people to wait around to die from a horrible disease, simply because one can’t make a profit developing a cure? Doesn’t it make more sense to invest our spare change, regardless if we make money or lose it, but so that we have a pretty decent chance for a cure in 5, 10 or 15 years?”
The study in the link for today paints a grim picture of the danger of how we live in our society. Switch off your internet at 9 pm, dim the lights at 10 and go sleep, the unpaid bills and unfinished projects will be waiting for you the next day.
A momentous scientific study focused on early detection of Alzheimer’s disease, and tracking it over time, seeks healthy volunteers without memory problems, as well as people who have mild memory problems and those who have been diagnosed with mild dementia due to Alzheimer’s disease.
Potential study volunteers can learn more by visiting www.ADNI3.org or by calling 1-888-2-ADNI-95 (1-888-223-6495).
In the next three minutes, three people will develop Alzheimer’s disease. Two of them will be women.
There are 5.7 million Alzheimer’s patients in the United States. By 2050, there will probably be as many as 14 million, and twice as many women as men will have the disease.
And yet research into “women’s health” remains largely focused on reproductive fitness and breast cancer. We need to be paying much more attention to the most important aspect of any woman’s future: her ability to think, to recall, to imagine — her brain.
In a first-of-its-kind study, researchers have found that in people middle-aged and older, a brain structure that is key to learning and memory is plumpest in those who spend the most time standing up and moving. At every age, prolonged sitters show less thickness in the medial temporal lobe and the subregions that make it up, the study found.
Scientists have recently made a major discovery that could lead to a breakthrough in the treatment of Alzheimer’s disease. A recent study published in Nature Medicine reports that researchers were able to identify the primary genetic risk factor the development of the disease, and they even figured out a potential way to neutralize the risk factor.
Funny play on words from the authors from Phys.org but the topic is serious enough.
A compound in beets that gives the vegetable its distinctive red color could eventually help slow the accumulation of misfolded proteins in the brain, a process that is associated with Alzheimer’s disease. Scientists say this discovery could lead to the development of drugs that could alleviate some of the long-term effects of the disease, the world’s leading cause of dementia.
The current Alzheimer’s clinical research impasse has encouraged more doctors to pursue non-pharmacological alternatives. For most individuals — beyond the up-to-5-percent who are genetically predisposed to early onset Alzheimer’s — focusing on lifestyle factors as the key to brain fitness and cognitive function, they say, is wiser than waiting for a breakthrough delivered in a pill.
A new study from The University of Texas Medical Branch at Galveston shows that using near infrared light on the heads of mice can effectively reduce vulnerability to the damaging effects of a toxic chemical in the brain known to be involved with the onset of Alzheimer’s. This data is detailed in Scientific Reports.
In March 2015, Li-Huei Tsai set up a tiny disco for some of the mice in her laboratory. For an hour each day, she placed them in a box lit only by a flickering strobe. The mice — which had been engineered to produce plaques of the peptide amyloid-β in the brain, a hallmark of Alzheimer’s disease — crawled about curiously. When Tsai later dissected them, those that had been to the mini dance parties had significantly lower levels of plaque than mice that had spent the same time in the dark1.