Know the signs and talk about it

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A survey released this week by the Alzheimer’s Association finds that nearly 90 percent of Americans say they would want others to tell them if they were showing signs of memory loss or other symptoms of dementia. And yet, nearly three quarters of Americans say having that conversation would be “challenging” for them.

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Alzheimer’s Facts and Statistics for 2019: Everything You Need to Know

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The 2019 Alzheimer’s Disease Facts and Figures Report reveals that one in 10 Americans age 65 or older have Alzheimer’s disease. While researchers look for an Alzheimer’s cure, the Alzheimer’s Drug Discovery Foundation (ADDF) recently awarded $3.5 million to researchers focused on promising early-detection Alzheimer’s tests ranging from blood tests to eye tests that can diagnose Alzheimer’s early and affordably. The latest Alzheimer’s disease facts and statistics illustrate why researchers are determined to find a cure or halt the disease’s progression. Ahead, some interesting facts about Alzheimer’s, and your guide to the most common questions.

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Status of Alzheimer’s research

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There are roughly 326 active, recruiting or enrolling by invitation clinical trials on the elusive disease, per clinicaltrial.gov. The U.S. last year dramatically stepped up funding for Alzheimer’s disease research, from $400 million a year to over $2 billion annually, although the Alzheimer’s Association says more is needed.

The biggest problem: Scientists still don’t know the cause of Alzheimer’s.

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Risk of Alzheimer’s when it hits extended family members

Alzheimer; News from the web:

In line with previous studies, the researchers found that having one or more first-degree relatives with Alzheimer’s put people at significantly higher risk for the disease. People with one first-degree relative with Alzheimer’s were 1.73 times more likely to develop the disease. Looking further into the family tree, people with two first-degree relatives with Alzheimer’s were nearly four times more likely to develop the disease. Those with three first-degree relatives were nearly two-and-half more times likely, and those with four were almost 15 times more likely to develop Alzheimer’s disease.

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Accelerating Alzheimer’s research

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A team of researchers at the Human Computation Institute and Cornell University seek to understand what causes a 30% reduction of blood flow to the brain in Alzheimer’s patients.

Preliminary findings from the Schaffer-Nishimura Biomedical Engineering Lab suggest that restoring blood flow to the brain could delay the onset of Alzheimer’s and restore cognitive functioning. But there is too much data to sift through, and the blood flow imagery is too subtle for most algorithms to classify into capillaries that are either flowing or stalled. So instead, citizen scientists are helping analyze the videos in a gamified effort called “Stall Catchers” — and, through this crowdsourcing effort, are doing so at a much faster rate than the lab.

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Play the game to help research HERE

Light on Alzheimer’s

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In 2016, to the surprise of Alzheimer’s disease researchers across the world, a team at the Massachusetts Institute of Technology found that setting mice in front of a blinking light could clear out the characteristic protein plaques thought to be one of the roots of the disease. A recent follow up study found that sounds played at a particular frequency clearned plaques and improved cognition, as well.

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We can’t control aging, genetics. That leaves lifestyle

Alzheimer; News from the web:

Let’s start with a hard truth: While certain FDA-approved drugs can treat the symptoms, no cures or treatments have been shown to stop, slow or reverse the progression of Alzheimer’s disease, the most common form of dementia. The FDA is clamping down on the makers of dozens of products, often labelled as dietary supplements, that claim otherwise. What those companies are selling, says the administration, is false hope.

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A pill from down-under for alzheimer’s?

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The hopeful quote:


“We have reason to believe that not only can it reverse the effects of Alzheimer’s, but possibly prevent the effects from occurring in the beginning,” Dr Hatchuel said.
“It has the potential to change the lives of 50 million people across the world, which is absolutely ground breaking.”

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Failed trial

Alzheimer; News from the web:

The companies developing aducanumab, Biogen and its partner Eisai, announced that they halted two late-stage trials of the experimental drug after an independent group’s analysis showed that the trials were unlikely to “meet their primary endpoint.”

The Cambridge, Massachusetts-based biotech giant joins a long list of companies in the last decade that have failed to find a treatment for Alzheimer’s.

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