Large Alzheimer’s study moves forward despite the pandemic

Alzheimer; News from the web:

Where lots of studies have been halted due to the pandemic, the large study at the the Institute for Memory Impairments and Neurological Disorders at the University of California, Irvine is moving forward cautiously.

Read the article in our link for today to learn about how they assure the safety of the participants in the study.

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sleep apnea and Alzheimer’s

Alzheimer; News from the web:

New research seems to suggest that both cause the same brain damage.

A new study confirms links between obstructive sleep apnea and Alzheimer’s disease. Possible reasons for the association include the build up of toxic products due to lack of oxygen.

Equipment to be used for people with sleep apnea

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Alzheimer’s and Immunotherapy

Alzheimer; News from the web:

Immunotherapy is the prevention or treatment of disease with drugs that stimulate an immune response. Scientists are looking for a cure to Alzheimer’s disease that boosts our immune systems. Administering drugs to elicit an immune response works in a similar way to a vaccine and pharmaceutical companies are placing bets on immunotherapy to target Alzheimer’s disease.

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vascular risk factors and subsequent Alzheimer’s disease

Alzheimer; News from the web:

The clinical guidelines related to the primary prevention of Alzheimer’s disease (AD) have focused on the management of vascular risk factors. However, the link between vascular risk factors and AD in older adults remains unclear. This study aimed to determine the association between vascular risk factors and subsequent AD in 178,586 older adults (age ≥ 65 years).

alzres.biomedcentral.com

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The gender gap with Alzheimer’s

Alzheimer; News from the web:

Why are women diagnosed more with Alzheimer’s than men?

One study found menopause, which reduces estrogen levels in a women’s body, may be to blame. Scientists scanned the brains of women and men and found declines in estrogen were involved in Alzheimer’s abnormalities.

Another recent report found women with more belly fat had a higher risk for dementia than men with the same issue. Specifically, women with a higher waist circumference had a 39% increased risk of dementia in 15 years.

And researchers recently performed brain scans on more than 1,000 older adults and found women metabolized sugar better, which may help them compensate for dementia damage better causing a delayed diagnosis.

www.news4jax.com

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research finds antidepressants may reduce signs of Alzheimer’s

Alzheimer; News from the web:

A new study from a Penn researcher adds to evidence that a class of antidepressant drugs known as SSRIs may reduce production of a key protein found in the brains of people with Alzheimer’s disease. This is evidence, she said, that the drugs could someday be part of a cocktail used to prevent or delay this form of dementia.

www.inquirer.com

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Artificial Intelligence and Alzheimer’s

Alzheimer; News from the web:

A team led by Dr Laura Ferraiuolo of The University of Sheffield have found that AI could be used to assess and monitor potential patients. Specifically, machines could be programmed to recognise Alzheimer’s by looking at an image of a patient’s brain, as well as assessing their movements and speech to determine if they are likely to be suffering from the condition before symptoms progress.

http://forgetoday.com/

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Navigation trouble could be a signal

Alzheimer; News from the web:

Researchers compared the navigation performance of 202 volunteers without genetic Alzheimer’s risk and 65 volunteers with increased genetic risk. The latter had a specific expression of the gene for apolipoprotein E, the APOE-ε4 allele.

Source:
Ruhr-Universitaet-Bochum
Journal reference:
Bierbrauer, A., et al. (2020) Unmasking selective path integration deficits in Alzheimer’s disease risk carriers. Science Advances. doi.org/10.1126/sciadv.aba1394.

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A better test for Alzheimer’s

Alzheimer; News from the web:

Clinical trials of Alzheimer’s medicines have failed frequently but now researchers believe that this may have been caused by the drugs given too late. So if they could just develop a test that would detect Alzheimer’s earlier, it would make the drugs that have failed for use later in the process, so much more productive.

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Inflammatory bowel disease may increase risk for dementia

Alzheimer; News from the web:

A new study found that Individuals with inflammatory bowel disease were at greatest risk for two types of dementia: Alzheimer’s dementia, which is caused by damage and death to nerve cells and affects memory, thinking and behavior; and vascular dementia, which stems from conditions that block or reduce blood flow to the brain.

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Being poor impacts Alzheimer’s risk

Alzheimer; News from the web:

A new study shows that those living in the poorest neighborhoods had the highest risk for brain changes commonly related to Alzheimer’s risk. For each one-point increase on the scale of socioeconomic deprivation, there was an 8 percent increase in the odds for Alzheimer’s brain pathology. 

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Always think Positive

Alzheimer; News from the web:

Persistent negative thinking patterns may raise the risk of Alzheimer’s disease, according to a new study.

In a study of people over the age of 55, researchers found repetitive negative thinking (RNT) is linked to subsequent cognitive decline, as well as the deposition of harmful brain proteins linked to Alzheimer’s.

The researchers say RNT should now be further investigated as a potential risk factor for dementia, and psychological tools, such as mindfulness or meditation, should be studied to see if these could reduce dementia risk.

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Life style changes and Alzheimer’s

Alzheimer; News from the web:

The study will test the role of lifestyle changes in Alzheimer’s disease, specifically a combination of diet, physical activity, social activity and cognitive exercises. The study is based on a similar study done in Finland, that showed benefits in thinking and memory among participants who followed a specific set of behaviors. The US version is being specifically adapted to America’s diverse population.

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Alzheimer’s and Pollution

Alzheimer; News from the web:

  • Many recent studies show that Alzheimer’s disease occurs more often in people exposed to fine particles in polluted air.
  • Such droplets, a 30th the diameter of a human hair, contain several toxic substances that can damage brain cells.
  • Particles can weaken a protective barrier around the brain and also can enter from nerves near the nose.

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Sex and Alzheimer’s Disease

Alzheimer; News from the web:

According to the World Health Organization (WHO), over 50 million people have Alzheimer’s disease or related dementia, and these numbers are expected to double in the next 20 years. Recent studies have determined a gender predilection with the disease; as per the latest research, women have a higher risk of being affected by Alzheimer’s disease compared with men.

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