This drug may help if used before you get symptoms

Alzheimer; News from the web:

“I don’t want to raise false hopes,” Researcher Bloom said, but “if this idea of using memantine as a prophylactic pans out, it will be because we now understand that calcium is one of the agents that gets the disease started, and we may be able to stop or slow the process if done very early.”

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About hope

Alzheimer; News from the web:

Is it good to get our hopes up with every bit of good news, or is the disappointment when it turns out not to be the magic bullet too much?

A promising new drug called BAN2401 generated a lot of excitement after a clinical trial found it slowed the progression of Alzheimer’s by 30%, but recent revelations have left investors and doctors with more questions than answers, reports Bloomberg.

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Skinny-fat may indicate Alzheimer’s

Alzheimer; News from the web:

You can’t tell how healthy someone is just by looking at them, but that doesn’t mean people don’t make assumptions, especially when they’re factoring in weight. But what about people who are “skinny-fat”? According to a new study, this body type, which is characterized by a combination of high fat mass and low muscle mass, may actually be worse for your health than obesity alone.

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Will this turnaround be real??

Alzheimer; News from the web:

Biogen posts that BAN2401 met on the ADCOMS secondary endpoint measure in its phase 2 study treating patients with Alzheimer’s.

BAN2401 showed evidence that it could reduce the progression of Alzheimer’s.

The positive update for BAN2401 was a huge surprise, because the failure rate for creating a treatment for Alzheimer’s is 99.6%.

BAN2401 still has to go through a phase 3 study in order to prove that it works in treating patients with Alzheimer’s.

Biogen is not only relying on BAN2401 for Alzheimer’s treatment, it also has another drug in late-stage development for the disease known as Aducanumab.

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A common virus can cause Alzheimer’s?

Alzheimer; News from the web:

Strains of a virus that most people acquire in childhood may play a role in the development of Alzheimer’s disease later in life.

Research published June 21, 2018, in the scientific journal Neuron revealed that levels of two types of human herpes virus (HHV-6A and HHV-7) were twice as high in the brains of patients who died with Alzheimer’s disease compared with those who did not have the disease.

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Dyscalculia and Alzheimer’s

Alzheimer; News from the web:

Research into problems with mathematics in patients with Alzheimer’s

Dyscalculia is an early sign of AD. It should be included among the reliable clinical hallmarks for the diagnosis of Alzheimer’s Disease. Identification of dyscalculic symptoms in these patients requires composite assessment procedure.

Read all about it: HERE

 

High Blood pressure and dementia

Alzheimer; News from the web:

A new study indicates that patients with high blood pressure are at a higher risk of developing dementia. This research also shows (for the first time) that an MRI can be used to detect very early signatures of neurological damage in people with high blood pressure, before any symptoms of dementia occur.

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volunteers called

Alzheimer; News from the web:

Researchers are looking for seniors of all backgrounds, including healthy adults, people with mild memory complaints and people who have been diagnosed with the disease, said Dr. Michael Weiner, an internationally-recognized Alzheimer’s expert.

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Success with fruit flies!

Alzheimer; News from the web:

Researchers have reversed symptoms of Alzheimer’s disease in fruit flies by adjusting the production of certain enzymes. The finding may open doors to exploring epigenetics as a potential avenue for Alzheimer’s disease treatments

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Animal memory may help Alzheimer’s research

Alzheimer; News from the web:

Have you ever looked at your dog or cat and wondered whether it can remember that you recently rewarded or scolded them — and when that happened?

Indiana University neuroscientists have discovered what they say is the first evidence nonhuman animals can replay a stream of past events from memory — and even the sequence in which those events occurred.

The discovery of this type of episodic memory in rodents may someday help advance the development of new drugs to treat Alzheimer’s disease, said Jonathon Crystal, a professor and director of the neurosciences program at IU-Bloomington

Read all about it HERE