Status of Alzheimer’s research

Alzheimer; News from the web:

There are roughly 326 active, recruiting or enrolling by invitation clinical trials on the elusive disease, per clinicaltrial.gov. The U.S. last year dramatically stepped up funding for Alzheimer’s disease research, from $400 million a year to over $2 billion annually, although the Alzheimer’s Association says more is needed.

The biggest problem: Scientists still don’t know the cause of Alzheimer’s.

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Risk of Alzheimer’s when it hits extended family members

Alzheimer; News from the web:

In line with previous studies, the researchers found that having one or more first-degree relatives with Alzheimer’s put people at significantly higher risk for the disease. People with one first-degree relative with Alzheimer’s were 1.73 times more likely to develop the disease. Looking further into the family tree, people with two first-degree relatives with Alzheimer’s were nearly four times more likely to develop the disease. Those with three first-degree relatives were nearly two-and-half more times likely, and those with four were almost 15 times more likely to develop Alzheimer’s disease.

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Accelerating Alzheimer’s research

Alzheimer; News from the web:

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A team of researchers at the Human Computation Institute and Cornell University seek to understand what causes a 30% reduction of blood flow to the brain in Alzheimer’s patients.

Preliminary findings from the Schaffer-Nishimura Biomedical Engineering Lab suggest that restoring blood flow to the brain could delay the onset of Alzheimer’s and restore cognitive functioning. But there is too much data to sift through, and the blood flow imagery is too subtle for most algorithms to classify into capillaries that are either flowing or stalled. So instead, citizen scientists are helping analyze the videos in a gamified effort called “Stall Catchers” — and, through this crowdsourcing effort, are doing so at a much faster rate than the lab.

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Play the game to help research HERE

Light on Alzheimer’s

Alzheimer; News from the web:


In 2016, to the surprise of Alzheimer’s disease researchers across the world, a team at the Massachusetts Institute of Technology found that setting mice in front of a blinking light could clear out the characteristic protein plaques thought to be one of the roots of the disease. A recent follow up study found that sounds played at a particular frequency clearned plaques and improved cognition, as well.

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We can’t control aging, genetics. That leaves lifestyle

Alzheimer; News from the web:

Let’s start with a hard truth: While certain FDA-approved drugs can treat the symptoms, no cures or treatments have been shown to stop, slow or reverse the progression of Alzheimer’s disease, the most common form of dementia. The FDA is clamping down on the makers of dozens of products, often labelled as dietary supplements, that claim otherwise. What those companies are selling, says the administration, is false hope.

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A pill from down-under for alzheimer’s?

Alzheimer; News from the web:

The hopeful quote:


“We have reason to believe that not only can it reverse the effects of Alzheimer’s, but possibly prevent the effects from occurring in the beginning,” Dr Hatchuel said.
“It has the potential to change the lives of 50 million people across the world, which is absolutely ground breaking.”

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Failed trial

Alzheimer; News from the web:

The companies developing aducanumab, Biogen and its partner Eisai, announced that they halted two late-stage trials of the experimental drug after an independent group’s analysis showed that the trials were unlikely to “meet their primary endpoint.”

The Cambridge, Massachusetts-based biotech giant joins a long list of companies in the last decade that have failed to find a treatment for Alzheimer’s.

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Latest research findings on Alzheimer’s

Alzheimer; News from the web:

Next avenue has a great article about the latest theories concerning what causes Alzheimer’s. We link to it below. So far, the results have been beyond disappointing. A class of drugs called “acetylcholinesterase inhibitors” offer marginal functional improvements, but that’s been it. Things are starting to change, though.

Read all about it HERE

A new study and here is what the researchers say:

Alzheimer; News from the web:

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“It would be nice if we could draw a blood test when you’re 50 or 60, monitor you every five years, be alerted of your amyloid levels, and a pill or infusion that’s going to help stave off Alzheimer’s,” said Joseph Shimon Kass, M.D., director of neurology at Baylor College of Medicine’s Alzheimer’s Disease and Memory Disorders Center. “We’re nowhere near that, but this study brings us closer to that possibility.”

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A pill to treat Alzheimer’s

Alzheimer; News from the web:

As powerful as the human brain is, once it’s damaged it can’t really recover completely. Now researchers at Penn State may have found a way to boost the brain’s regenerative abilities, using certain molecules to convert neighboring cells into new neurons. The technique could eventually lead to pills that treat brain injuries, stroke or Alzheimer’s disease.

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Alzheimer’s and hearing loss

Alzheimer; News from the web:

A new study says hearing may play a critical role in brain power. We often just think it’s frustrating when we can’t hear well or if you have a spouse or a loved one that you have to repeat things to a lot. But now, a new study in Alzheimer’s and Dementia shows hearing loss is linked to cognitive decline, especially if you don’t get something such as hearing aids to boost it.

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