Alzheimer; News from the web:
The first infusion of an investigational drug that aims to delay or help to prevent the earliest memory loss due to Alzheimer’s disease took place in September at Butler Hospital in Providence, R.I., researchers announced.
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Alzheimer; News from the web:
An interesting development is that apparently an experimental drug, aimed to help people with Alzheimer’s, could play a role in helping children with certain types of Autims. Read the full story in our link for today.
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Alzheimer; News from the web:
Clinical trials of Alzheimer’s medicines have failed frequently but now researchers believe that this may have been caused by the drugs given too late. So if they could just develop a test that would detect Alzheimer’s earlier, it would make the drugs that have failed for use later in the process, so much more productive.
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Alzheimer; News from the web:
This sounds like good news. Scientists have found a way to speed up the testing of Alzheimer’s drugs.
Alzheimer’s clinical trials may take decades, but a new discovery could cut clinical trial time down to a matter of weeks.
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Alzheimer; News from the web:
A laboratory study has found that the asthma drug salbutamol prevents the formation of tangles of fibrous protein that are a hallmark of Alzheimer’s disease. The next step will be to test the drug in animal models of the disease.
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Alzheimer; News from the web:
For this to hit the market: There are two drugs that have been developed by Salk Institute researchers to successfully treat Alzheimer’s in mice—and now, they have found that the very same drug compounds can also slow the aging process in the brains of healthy older mice.
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Alzheimer; News from the web:
Today we link to the article from Scientific American that tells the story about the reassessment of costs vs benefits for aducanumab.
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Alzheimer; News from the web:
Alzheimer’s disease affects some 5 million people in the United States, and as the population ages, doctors estimate those affected will more than double by 2050.
A new drug might offer new hope, WOWT reported.
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Alzheimer; News from the web:
Despite many promising leads, more than 120 drug treatments for Alzheimer’s disease have failed. But Cambridge-based biotech company Biogen revived hope on Tuesday with its announcement that it would seek Food and Drug Administration approval for a drug it abandoned earlier this year.
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Alzheimer; News from the web:
The biotech world went into a full-on frenzy Tuesday when drug giant Biogen dropped this whopper: The company is reviving its Alzheimer’s drug hopeful, aducanumab, after leaving it for dead all the way back in March. In fact, it’s marching forward with a Food and Drug Administration (FDA) application to approve the drug for certain patients facing cognitive decline.
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Alzheimer; News from the web:
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Alzheimer; News from the web:
An Alzheimer’s vaccine developed by a privately held Slovakian biotech firm showed early signs of efficacy in a mid-stage trial, a rare step forward in the fight against the brain-wasting disease, the company said on Monday.
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Alzheimer; News from the web:
Researchers have found that nilvadipine, a drug that doctors regularly use to treat hypertension, may help people with Alzheimer’s disease by increasing blood flow to the brain.
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Alzheimer; News from the web:
A cure for Alzheimer’s Disease does not exist just yet, but researchers at the University of New Mexico (UNM) are one step closer to finding one.
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Alzheimer; News from the web:
Treatment with blood pressure medication can improve blood flow to a key brain region in people with Alzheimer’s disease, a small clinical trial has found.
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Alzheimer; News from the web:
Alzheimer’s drugs cost seven times more than cancer drugs to develop
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Alzheimer; News from the web:
There are roughly 326 active, recruiting or enrolling by invitation clinical trials on the elusive disease, per clinicaltrial.gov. The U.S. last year dramatically stepped up funding for Alzheimer’s disease research, from $400 million a year to over $2 billion annually, although the Alzheimer’s Association says more is needed.
The biggest problem: Scientists still don’t know the cause of Alzheimer’s.
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Alzheimer; News from the web:
Here is a new drug that seemed effective for mice and now has been found safe for humans, so the next step it to test it on patients with Alzheimer’s. Exciting times
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Alzheimer; News from the web:
The companies developing aducanumab, Biogen and its partner Eisai, announced that they halted two late-stage trials of the experimental drug after an independent group’s analysis showed that the trials were unlikely to “meet their primary endpoint.”
The Cambridge, Massachusetts-based biotech giant joins a long list of companies in the last decade that have failed to find a treatment for Alzheimer’s.
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Alzheimer; News from the web:
Check out the project in the link for today. The claim is a novel process to find a way to immunize against Alzheimer’s disease. Not sure how this low budget will win from all the billions already spent by the large pharmaceutical companies but see for yourself.
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Alzheimer; News from the web:
Yes now we are at the stage that doctors are seriously think they may have found a way to prevent Alzheimer’s to happen. In May, doctors in New York will start testing a novel gene therapy
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Alzheimer; News from the web:
A new drug shows promising results: Early results indicate that the drug could reverse natural, age-related cognitive decline. Researchers also believe that it might help patients whose memories are impaired because of conditions such as depression, schizophrenia and Alzheimer’s disease.
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Alzheimer; News from the web:
Despite Roche’s recent trial failure for crenezumab, the ProMIS team remain confident a disease-modifying treatment will be found in the next decade.
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Alzheimer; News from the web:
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Alzheimer; News from the web:
The New York Times has a great article today, read it in our link below.
“The field is desperate, and we all want something to work,” said Dr. Reisa Sperling, director of the Center for Alzheimer Research and Treatment at Brigham and Women’s Hospital in Boston.
Read all about it HERE
(our blog will be on a short break to celebrate the US Thanksgiving, back on Monday)
Alzheimer; News from the web:
The NIHR University College London Hospitals (UCLH) Clinical Research Facility in the UK has initiated a clinical trial, DESPIAD, to assess a new treatment called miridesap for Alzheimer’s disease.
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Alzheimer; News from the web:
Good explanation of why it is so difficult to develop an Alzheimer’s drug and which one is leading the pack.
Expect next year some results about these hopeful developments.
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Alzheimer; News from the web:
Will take another decade to come and the development seems to cost about $10B
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Alzheimer; News from the web:
A new study from The University of Texas Medical Branch at Galveston has provided researchers important insights about an enzyme within the brain that plays a critical role in Alzheimer’s.
The UTMB researchers found that blocking the enzyme helped prevent memory loss in mice.
The enzyme is a promising target for developing medications to prevent cognitive decline. The study was recently published in Alzheimer’s and Dementia: Translational Research and Clinical Interventions.
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Alzheimer; News from the web:
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