Alzheimer; News from the web:
There are roughly 326 active, recruiting or enrolling by invitation clinical trials on the elusive disease, per clinicaltrial.gov. The U.S. last year dramatically stepped up funding for Alzheimer’s disease research, from $400 million a year to over $2 billion annually, although the Alzheimer’s Association says more is needed.
The biggest problem: Scientists still don’t know the cause of Alzheimer’s.
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Alzheimer; News from the web:
We now know early intervention could decrease the likelihood of more than one-third of dementia cases around the world. In fact, approximately 35% are attributed to nine modifiable risk factors, including high blood pressure, obesity and diabetes, hearing loss, smoking, depression, social interaction and lack of physical exercise. Therefore, monitoring which foods we eat, starting or continuing basic cardio and strength training programs, engaging the mind in the cognitive challenges and managing vascular risk factors all play demonstrable, critical roles in maintaining cognition before disease strikes.
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Alzheimer; News from the web:
In line with previous studies, the researchers found that having one or more first-degree relatives with Alzheimer’s put people at significantly higher risk for the disease. People with one first-degree relative with Alzheimer’s were 1.73 times more likely to develop the disease. Looking further into the family tree, people with two first-degree relatives with Alzheimer’s were nearly four times more likely to develop the disease. Those with three first-degree relatives were nearly two-and-half more times likely, and those with four were almost 15 times more likely to develop Alzheimer’s disease.
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Alzheimer; News from the web:
Here is a new drug that seemed effective for mice and now has been found safe for humans, so the next step it to test it on patients with Alzheimer’s. Exciting times
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Alzheimer; News from the web:
A newly described dementia strikes people in their last decades of life. The disease, aptly named LATE, comes with symptoms that resemble Alzheimer’s disease, but is thought to be caused by something completely different.
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Alzheimer; News from the web:
story
A team of researchers at the Human Computation Institute and Cornell University seek to understand what causes a 30% reduction of blood flow to the brain in Alzheimer’s patients.
Preliminary findings from the Schaffer-Nishimura Biomedical Engineering Lab suggest that restoring blood flow to the brain could delay the onset of Alzheimer’s and restore cognitive functioning. But there is too much data to sift through, and the blood flow imagery is too subtle for most algorithms to classify into capillaries that are either flowing or stalled. So instead, citizen scientists are helping analyze the videos in a gamified effort called “Stall Catchers” — and, through this crowdsourcing effort, are doing so at a much faster rate than the lab.
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Play the game to help research HERE
Alzheimer; News from the web:
In 2016, to the surprise of Alzheimer’s disease researchers across the world, a team at the Massachusetts Institute of Technology found that setting mice in front of a blinking light could clear out the characteristic protein plaques thought to be one of the roots of the disease. A recent follow up study found that sounds played at a particular frequency clearned plaques and improved cognition, as well.
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Alzheimer; News from the web:
Let’s start with a hard truth: While certain FDA-approved drugs can treat the symptoms, no cures or treatments have been shown to stop, slow or reverse the progression of Alzheimer’s disease, the most common form of dementia. The FDA is clamping down on the makers of dozens of products, often labelled as dietary supplements, that claim otherwise. What those companies are selling, says the administration, is false hope.
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Alzheimer; News from the web:
Alzheimer’s disease is a progressive, incurable brain disorder that slowly robs the sufferer of memory and cognitive functions, eventually claiming the ability to carry out even simple tasks.
Yet, it’s been noted that music can sometimes evoke responses from Alzheimer’s patients when nothing else can.
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Alzheimer; News from the web:
Here is new research that tells us that you can use a game to estimate your chances of getting Alzheimer’s.
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Alzheimer; News from the web:
NeuroTherapia Inc. will start clinical trials of a new drug targeting inflammation of the brain that’s found in Alzheimer’s and other neurological diseases, according to a news release.
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Alzheimer; News from the web:
story
The Springfield Museum of Art has joined the battle against dementia and Alzheimer’s disease with its In the Moment program.
Launched last fall, In the Moment lets families or caregivers join those afflicted with memory issues to take in the Museum’s exhibits, enjoy snacks and even create an art project together.
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Alzheimer; News from the web:
Just as genetic makeup plays a role in the risk for Alzheimer’s, new drugs designed to alter your genes could bring us closer to a cure.
The concept is called epigenetics, and one of the more promising drugs in this new avenue of Alzheimer’s research is now being studied in New Jersey.
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Alzheimer; News from the web:
Studies by National Journal of Physiology Pharmacy and Pharmacology and International Journal of School and Cognitive Psychology have shown a positive association between virgin coconut oil consumption and prevention of Alzheimer’s disease. Several studies have shown positive improvements in cognition, cognitive performance, orientation and semantic memory in individuals after intervention with virgin coconut oil.
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Alzheimer; News from the web:
Psychology today has a series about Alzheimer’s running, get the first part in our link for today.
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Alzheimer; News from the web:
Interesting read by readers digest.
How well you sleep could decrease—or raise—your chances of developing Alzheimer’s disease. Are your bedtime behaviors putting you at risk?
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Alzheimer; News from the web:
We have not tried this, please let us know how you experience it.
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Alzheimer; News from the web:
The hopeful quote:
“We have reason to believe that not only can it reverse the effects of Alzheimer’s, but possibly prevent the effects from occurring in the beginning,” Dr Hatchuel said.
“It has the potential to change the lives of 50 million people across the world, which is absolutely ground breaking.”
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Alzheimer; News from the web:
Most people with dementia have a number of brain abnormalities, not just Alzheimer’s disease. The finding is forcing scientists to rethink the search for treatments.
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Alzheimer; News from the web:
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Alzheimer; News from the web:
Read the latest post on Bill Gates’ blog about new ways to diagnose Alzheimer’s
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Alzheimer; News from the web:
New research at the University of Warwick is now underway to “prove” how curcumin can induce autophagy to prevent Alzheimer’s, after initial tests showed positive results.
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Alzheimer; News from the web:
You Asked, We Got the Answers: Disruptive Alzheimer’s Behavior, Confusing Diagnoses, Supplements and Clinical Trials From the website Being Patient
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Alzheimer; News from the web:
A new study shows that the part of your brain responsible for ASMR (
Autonomous Sensory Meridian Response ) doesn’t get lost to Alzheimer’s. Alzheimer’s tends to put people into layers of confusion, and the study confirms that music can sometimes actually lift people out of the Alzheimer’s haze and bring them back to (at least a semblance of) normality… if only for a short while.
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Alzheimer; News from the web:
The companies developing aducanumab, Biogen and its partner Eisai, announced that they halted two late-stage trials of the experimental drug after an independent group’s analysis showed that the trials were unlikely to “meet their primary endpoint.”
The Cambridge, Massachusetts-based biotech giant joins a long list of companies in the last decade that have failed to find a treatment for Alzheimer’s.
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