Researchers identified a brain protein that appears to help the disease spread between neurons, opening a potential new avenue for future treatments.

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Being diagnosed with Alzheimer’s disease can bring a range of emotions: Shock, anger, fear, and grief are all common. You might also feel a sense of relief and acceptance now that you have a better understanding of what’s happening with your mind. At the same time, denial can creep in, often fueled by the stigma that exists around the disease. Stigma often stems from fear and a lack of public awareness, and reframing how society views the condition is essential to improving quality of life. 

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This episode of “Tomorrow’s Cure” features Oana Dumitrascu, M.D., a vascular neurologist at Mayo Clinic in Arizona, and Yalin Wang, Ph.D., program chair of the Computer Science Graduate Programs in the School of Computing and Augmented Intelligence at Arizona State University, as they discuss a new, noninvasive approach to learning more about Alzheimer’s disease.

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The sheer volume of biological data available, including genomic, protein, metabolic, and microbiome signatures, is impossible for researchers to make sense of on their own. Advances in AI technology, however, are allowing them to begin to interrogate this data for new clues about Alzheimer’s.

An MIT-based team developed an AI foundation model, an algorithm trained on vast datasets that can do many specialized tasks, called FINGERS-7B. The name references the FINGER dataset it was trained on — one of the largest lifestyle prevention trials that combines exercise, diet, and cognitive training — and the seven billion parameters, the number of internal dials and levers controlling the behavior of the model. 

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Women with Parkinson’s disease may be more vulnerable to Alzheimer’s-related changes in the brain than men, according to new research presented at the European Academy of Neurology (EAN) Congress 2026. Parkinson’s disease and Alzheimer’s disease frequently co-occur in older adults, yet sex differences in Alzheimer’s-related pathology among people with Parkinson’s disease remain underexplored.

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• An anti-inflammatory diet may lower dementia risk, even with early dementia biomarkers.
• People with common precursors for Alzheimer’s disease had a 21% or more lower risk when eating an anti-inflammatory diet.
• Eating more fruits, veggies, legumes, whole grains and nuts supports brain health and reduces inflammation.

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