Alzheimer; News from the web:
Here is a new drug that seemed effective for mice and now has been found safe for humans, so the next step it to test it on patients with Alzheimer’s. Exciting times
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Alzheimer; News from the web:
In 2016, to the surprise of Alzheimer’s disease researchers across the world, a team at the Massachusetts Institute of Technology found that setting mice in front of a blinking light could clear out the characteristic protein plaques thought to be one of the roots of the disease. A recent follow up study found that sounds played at a particular frequency clearned plaques and improved cognition, as well.
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Alzheimer; News from the web:
Let’s start with a hard truth: While certain FDA-approved drugs can treat the symptoms, no cures or treatments have been shown to stop, slow or reverse the progression of Alzheimer’s disease, the most common form of dementia. The FDA is clamping down on the makers of dozens of products, often labelled as dietary supplements, that claim otherwise. What those companies are selling, says the administration, is false hope.
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Alzheimer; News from the web:
Alzheimer’s disease is a progressive, incurable brain disorder that slowly robs the sufferer of memory and cognitive functions, eventually claiming the ability to carry out even simple tasks.
Yet, it’s been noted that music can sometimes evoke responses from Alzheimer’s patients when nothing else can.
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Alzheimer; News from the web:
NeuroTherapia Inc. will start clinical trials of a new drug targeting inflammation of the brain that’s found in Alzheimer’s and other neurological diseases, according to a news release.
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Alzheimer; News from the web:
Just as genetic makeup plays a role in the risk for Alzheimer’s, new drugs designed to alter your genes could bring us closer to a cure.
The concept is called epigenetics, and one of the more promising drugs in this new avenue of Alzheimer’s research is now being studied in New Jersey.
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Alzheimer; News from the web:
The hopeful quote:
“We have reason to believe that not only can it reverse the effects of Alzheimer’s, but possibly prevent the effects from occurring in the beginning,” Dr Hatchuel said.
“It has the potential to change the lives of 50 million people across the world, which is absolutely ground breaking.”
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Alzheimer; News from the web:
Most people with dementia have a number of brain abnormalities, not just Alzheimer’s disease. The finding is forcing scientists to rethink the search for treatments.
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Alzheimer; News from the web:
New research at the University of Warwick is now underway to “prove” how curcumin can induce autophagy to prevent Alzheimer’s, after initial tests showed positive results.
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Alzheimer; News from the web:
As powerful as the human brain is, once it’s damaged it can’t really recover completely. Now researchers at Penn State may have found a way to boost the brain’s regenerative abilities, using certain molecules to convert neighboring cells into new neurons. The technique could eventually lead to pills that treat brain injuries, stroke or Alzheimer’s disease.
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Alzheimer; News from the web:
Despite Roche’s recent trial failure for crenezumab, the ProMIS team remain confident a disease-modifying treatment will be found in the next decade.
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Alzheimer; News from the web:
In a small lab in Jackson Hole, Wyo., 65-year-old Paul Cox believes he’s closing in on a treatment that might prevent Alzheimer’s disease. And ALS. And a host of other neurodegenerative diseases, for that matter. Cox, we should point out, isn’t a neurologist. He isn’t a physician of any kind. He doesn’t work at a big drug company or an academic medical center or a government laboratory. His ideas come from so far outside the mainstream of neurological research that you might think he’s crazy or deluded or worse. But then, some very credible people think he might be on to something big—which might make the improbable, quixotic story you are about to read one of the most important as well.
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Alzheimer; News from the web:
Whether royal jelly has genuine health benefits for humans is a matter for more research, but in a study scientists have cracked one of the most enduring puzzles surrounding the milky gloop: the secret behind its queen-maker magic.
The discovery promises to have an impact far beyond the niche field of melittology. Armed with the findings, scientists are now exploring potential new treatments for wounds and disorders such as muscle wastage and neurodegenerative disease.
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Alzheimer; News from the web:
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Alzheimer; News from the web:
The New York Times has a great article today, read it in our link below.
“The field is desperate, and we all want something to work,” said Dr. Reisa Sperling, director of the Center for Alzheimer Research and Treatment at Brigham and Women’s Hospital in Boston.
Read all about it HERE
(our blog will be on a short break to celebrate the US Thanksgiving, back on Monday)
Alzheimer; News from the web:
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Alzheimer; News from the web:
Readers digest shares this nice list of things you can do to keep Alzheimer’s under control or away.
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Alzheimer; News from the web:
A Chinese company, Green Valley Pharmaceutical, has achieved the rare feat of getting a positive read-out in a Phase III trial in mild-to-moderate Alzheimer’s disease.
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Alzheimer; News from the web:
Medics have been undertaking tests to determine whether antidepressants can be used to treat Alzheimer’s disease, a condition for which there is no cure. The results to date are encouraging.
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Alzheimer; News from the web:
This is the most important column I’ve ever written. The message is quite complex–dozens of new health parameters to test for and to optimize, all of them interacting in ways that will require new training for MDs. The message is also as simple as it can be: There is a cure for Alzheimer’s disease. You can stop reading right here, and buy two copies of Dale Bredesen’s book, one for you and one for your doctor: The End of Alzheimer’s.
Read all about it HERE
Alzheimer; News from the web:
The NIHR University College London Hospitals (UCLH) Clinical Research Facility in the UK has initiated a clinical trial, DESPIAD, to assess a new treatment called miridesap for Alzheimer’s disease.
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Alzheimer; News from the web:
Check out the the Wisconsin Alzheimer’s Institute’s Amazing Grace Chorus.
And in Houston Texas we also have a small but great initiative choir see them in the link for today.
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Alzheimer; News from the web:
Scientists at the University of Texas have implicated a type of cellular stress for the first time as a player in Alzheimer’s disease. And their discovery could lead to treatments for more than 20 human brain diseases including Alzheimer’s and traumatic brain injury.
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Alzheimer; News from the web:
A study by a Massachusetts General Hospital (MGH) research team finds that neurogenesis -inducing the production of new neurons — in the brain structure in which memories are encoded can improve cognitive function in a mouse model of Alzheimer’s disease. Their investigation shows that those beneficial effects on cognition can be blocked by the hostile inflammatory environment present in the brain of patients with Alzheimer’s disease and that physical exercise can “clean up” the environment, allowing new nerve cells to survive and thrive and improving cognition in the Alzheimer’s mice.
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Alzheimer; News from the web:
Is it good to get our hopes up with every bit of good news, or is the disappointment when it turns out not to be the magic bullet too much?
A promising new drug called BAN2401 generated a lot of excitement after a clinical trial found it slowed the progression of Alzheimer’s by 30%, but recent revelations have left investors and doctors with more questions than answers, reports Bloomberg.
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Alzheimer; News from the web:
Good explanation of why it is so difficult to develop an Alzheimer’s drug and which one is leading the pack.
Expect next year some results about these hopeful developments.
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Alzheimer; News from the web:
Listen to this NPR program that helps caretakers to find tips and exchange experiences.
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Alzheimer; News from the web:
Researchers say a type of iron called magnetite shows up in the brains of people with Alzheimer’s. Figuring out why could lead to new treatments for the disease.
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Alzheimer; News from the web:
With two of the last drug-makers abandoning their late stage trials, the familiar question comes up again: Why would you want to know if you have Alzheimer’s when there is no cure? The opinions are divided.
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