Category Archives: Treatment

New Tool That Tracks How the Brain Removes Waste Could Offer Clues About Alzheimer’s

Posted on by

The gold standard for studying movement within neurological networks involves injecting tracer substances into cerebrospinal fluid, the liquid surrounding the brain and spinal cord. But due to the extra volume introduced to the brain system, extra fluid can disrupt normal brain processes and often produces only a broad picture of fluid flow rather than highlighting pathways that could be linked to neurological disease.

“These injected tracers disturb the very system we’re attempting to measure,” said Yang. “We wanted to find a better way.”

Read more HERE

What Your Genetic Risk For Alzheimer’s Means

Posted on by

Scientists have long known that genetics play a role in Alzheimer’s disease risk. Some genetic markers appear to increase the likelihood of developing the condition, while others seem to offer a degree of protection against cognitive decline and brain aging.

One of the most important genes researchers study is called APOE. Everyone inherits two copies, but the specific version you carry may influence how resilient your brain is over time. In particular, one version called APOE4 is strongly linked to a higher risk of Alzheimer’s disease, while another, APOE2, is associated with lower risk and even exceptional longevity.

Now, new research may help explain why (and why some may be more resilient to aging than others).

Read more HERE

Lithium’s Surprising Effect on Alzheimer’s

Posted on by

Scientists have identified new ways lithium chloride may interact with Alzheimer’s disease mechanisms at the cellular level.

A new study from the University of Eastern Finland (UEF) suggests lithium chloride may influence several cellular processes linked to Alzheimer’s disease.

Alzheimer’s disease (AD) is the most common type of dementia. One of its key features is the abnormal phosphorylation and buildup of Tau proteins inside brain cells, along with the accumulation of β-amyloid (Aβ) plaques.

Researchers have previously used lithium salts, especially lithium chloride and lithium carbonate, in cell and animal models of AD to reduce Tau hyperphosphorylation and aggregation. However, human clinical trials have produced inconsistent results, with some studies showing little or no improvement in cognitive function.

Read more HERE

Scientists reverse Alzheimer’s in mice with breakthrough nanotechnology

Posted on by

A new nanotechnology treatment reversed Alzheimer’s symptoms in mice by restoring the brain’s natural cleanup system. The specially engineered nanoparticles helped clear toxic amyloid proteins from the brain and repair the blood-brain barrier, which normally protects and regulates the brain’s environment. In one striking experiment, elderly mice treated with the therapy later behaved like healthy younger mice.

Read more HERE

FDA Approves First Non-Antipsychotic Drug to Treat Agitation Associated with Dementia

Posted on by

The U.S. Food and Drug Administration today approved an expanded use for Auvelity (dextromethorphan hydrobromide and bupropion hydrochloride) extended-release tablets to treat agitation associated with dementia due to Alzheimer’s disease in adults. The drug is the first FDA-approved treatment for this condition that is not an antipsychotic. FDA initially approved Auvelity in 2022 to treat major depressive disorder in adults.

Read more HERE