FDA does not approve new Alzheimer’s drug

Alzheimer; News from the web:

Government health advisers sharply criticized a closely watched Alzheimer’s drug on Friday, concluding there wasn’t enough evidence that the experimental drug slowed the brain-destroying disease.

The panel of outside experts for the Food and Drug Administration agreed that a pivotal study in patients failed to show “strong evidence” that the drug worked. The experts warned of multiple “red flags” with the data, which did not initially show any benefit until another analysis with later results.

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research finds antidepressants may reduce signs of Alzheimer’s

Alzheimer; News from the web:

A new study from a Penn researcher adds to evidence that a class of antidepressant drugs known as SSRIs may reduce production of a key protein found in the brains of people with Alzheimer’s disease. This is evidence, she said, that the drugs could someday be part of a cocktail used to prevent or delay this form of dementia.

www.inquirer.com

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Tea, oranges and Broccoli will keep Alzheimer’s at bay

Alzheimer; News from the web:

A new study published in the journal Neurology in January 2020 concludes that increasing the intake of plant flavonols steeply reduces the risk of Alzheimer’s dementia (AD) by up to a half. In other words, AD could be prevented in many people simply by regularly eating and drinking more foods containing these compounds such as tea, oranges and broccoli.

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That new medicine for Alzheimer’s

Alzheimer; News from the web:

The biotech world went into a full-on frenzy Tuesday when drug giant Biogen dropped this whopper: The company is reviving its Alzheimer’s drug hopeful, aducanumab, after leaving it for dead all the way back in March. In fact, it’s marching forward with a Food and Drug Administration (FDA) application to approve the drug for certain patients facing cognitive decline.

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New option in the fight against Alzheimer’s

Alzheimer; News from the web:

Researchers have now found that slower loss of cognitive skills in people with AD correlates with higher levels of a protein that helps immune cells clear plaque-like cellular debris from the brain [1]. The efficiency of this clean-up process in the brain can be measured via fragments of the protein that shed into the cerebrospinal fluid (CSF). This suggests that the protein, called TREM2, and the immune system as a whole, may be promising targets to help fight Alzheimer’s disease.

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No Wait, it works!

Alzheimer; News from the web:

The drug company Biogen is asking the FDA to approve one of its Alzheimer’s treatments, a sign that clinical trials have shown success for the therapy. The drug, aducanumab, is still in the experimental stages, and Biogen had thrown in the towel months ago when studies didn’t seem to show progress. The company now says higher doses may be key. An Alzheimer’s drug gaining FDA approval would be blockbuster. There are currently no effective treatments for the memory-robbing disease, which affects more than 5 million people in the U.S. alone

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A possible treatment

Alzheimer; News from the web:

Scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) have identified a possible treatment for Alzheimer’s disease. Working together with a scientific team at the Rockefeller University in New York, the investigators have shown that treatment with the oral anticoagulant dabigatran delays the appearance of Alzheimer’s disease in mice.

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