Alzheimer; News from the web:
The first infusion of an investigational drug that aims to delay or help to prevent the earliest memory loss due to Alzheimer’s disease took place in September at Butler Hospital in Providence, R.I., researchers announced.
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Alzheimer; News from the web:
A new study from a Penn researcher adds to evidence that a class of antidepressant drugs known as SSRIs may reduce production of a key protein found in the brains of people with Alzheimer’s disease. This is evidence, she said, that the drugs could someday be part of a cocktail used to prevent or delay this form of dementia.
www.inquirer.com
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Alzheimer; News from the web:
The first drug shown to potentially delay the progression of Alzheimer’s disease could be approved next year.
The Food and Drug Administration (FDA) in the United States said that aducanumab had been accepted for a priority review process.
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Alzheimer; News from the web:
Scientists discover for the first time that oxytocin could be a potential new therapeutic option for cognitive disorders such as Alzheimer’s disease.
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Alzheimer; News from the web:
This sounds like good news. Scientists have found a way to speed up the testing of Alzheimer’s drugs.
Alzheimer’s clinical trials may take decades, but a new discovery could cut clinical trial time down to a matter of weeks.
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Alzheimer; News from the web:
A laboratory study has found that the asthma drug salbutamol prevents the formation of tangles of fibrous protein that are a hallmark of Alzheimer’s disease. The next step will be to test the drug in animal models of the disease.
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Alzheimer; News from the web:
The Alzheimer’s foundation provides a helpline for caregivers in over 90 languages!
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Alzheimer; News from the web:
A team of scientists from the Georgia Institute of Technology in Atlanta has discovered some reasons why lights flickering at 40 beats per second, or 40 hertz (Hz), have a beneficial effect on Alzheimer’s disease.
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Alzheimer; News from the web:
A new study published in the journal Neurology in January 2020 concludes that increasing the intake of plant flavonols steeply reduces the risk of Alzheimer’s dementia (AD) by up to a half. In other words, AD could be prevented in many people simply by regularly eating and drinking more foods containing these compounds such as tea, oranges and broccoli.
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Alzheimer; News from the web:
Lithium is well known in the treatment of psychiatric conditions and now researchers have found that a micro dose of it can be beneficial in the treatment of Alzheimer’s, even in later stages of the disease.
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Alzheimer; News from the web:
Studies by researchers at the Lighting Research Center at Rensselaer Polytechnic Institute in New York showed that light therapy tailored to increase the circadian stimulation during the day benefited individuals with Alzheimer’s disease or dementia living in long-term care settings.
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Alzheimer; News from the web:
For this to hit the market: There are two drugs that have been developed by Salk Institute researchers to successfully treat Alzheimer’s in mice—and now, they have found that the very same drug compounds can also slow the aging process in the brains of healthy older mice.
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Alzheimer; News from the web:
Hmm there is some support for this but the case does not seem to be very strong.
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Alzheimer; News from the web:
The biotech world went into a full-on frenzy Tuesday when drug giant Biogen dropped this whopper: The company is reviving its Alzheimer’s drug hopeful, aducanumab, after leaving it for dead all the way back in March. In fact, it’s marching forward with a Food and Drug Administration (FDA) application to approve the drug for certain patients facing cognitive decline.
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Alzheimer; News from the web:
Alzheimer’s symptoms are diminishing due to a treatment with ultrasound to allow medicine to get through the blood-brain barrier.
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Alzheimer; News from the web:
This article from the Guardian brings us five ways to slow down Alzheimer’s onset. For details see the article in our link for today.
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Alzheimer; News from the web:
Researchers have now found that slower loss of cognitive skills in people with AD correlates with higher levels of a protein that helps immune cells clear plaque-like cellular debris from the brain [1]. The efficiency of this clean-up process in the brain can be measured via fragments of the protein that shed into the cerebrospinal fluid (CSF). This suggests that the protein, called TREM2, and the immune system as a whole, may be promising targets to help fight Alzheimer’s disease.
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Alzheimer; News from the web:
A Birmingham nonprofit organization connects Alzheimer’s, dementia patients with art, see it in our link for today.
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Alzheimer; News from the web:
The drug company Biogen is asking the FDA to approve one of its Alzheimer’s treatments, a sign that clinical trials have shown success for the therapy. The drug, aducanumab, is still in the experimental stages, and Biogen had thrown in the towel months ago when studies didn’t seem to show progress. The company now says higher doses may be key. An Alzheimer’s drug gaining FDA approval would be blockbuster. There are currently no effective treatments for the memory-robbing disease, which affects more than 5 million people in the U.S. alone
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Alzheimer; News from the web:
Scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) have identified a possible treatment for Alzheimer’s disease. Working together with a scientific team at the Rockefeller University in New York, the investigators have shown that treatment with the oral anticoagulant dabigatran delays the appearance of Alzheimer’s disease in mice.
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Alzheimer; News from the web:
An open-label clinical trial working with eight people with Alzheimer’s disease concluded that a new wearable device that emits electromagnetic impulses was able to significantly improve memory loss in seven of these participants within 2 months.
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Alzheimer; News from the web:
The only way to fight off Alzheimer’s is called:
SHIELD
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Alzheimer; News from the web:
Read the story about how the FDA and their approval system can get in the way of treatments that have shown to be effective in other countries and seem safe to use.
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Alzheimer; News from the web:
Good article by the LA Times and they review the failed drug tests and then go into what will actually work to stave off Alzheimer’s without providing a real cure, but just the best practices we now know.
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Alzheimer; News from the web:
Read the heartwarming story of how people with dementia can relive their past by biking through familiar places, or exploring new ones, while not leaving their home.
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Alzheimer; News from the web:
Researchers have found that nilvadipine, a drug that doctors regularly use to treat hypertension, may help people with Alzheimer’s disease by increasing blood flow to the brain.
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Alzheimer; News from the web:
Alzheimer’s drugs cost seven times more than cancer drugs to develop
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Alzheimer; News from the web:
Here is a new drug that seemed effective for mice and now has been found safe for humans, so the next step it to test it on patients with Alzheimer’s. Exciting times
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Alzheimer; News from the web:
In 2016, to the surprise of Alzheimer’s disease researchers across the world, a team at the Massachusetts Institute of Technology found that setting mice in front of a blinking light could clear out the characteristic protein plaques thought to be one of the roots of the disease. A recent follow up study found that sounds played at a particular frequency clearned plaques and improved cognition, as well.
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