Diagnoses of cognitive impairment and dementia should be based on symptoms and functional effects rather than biomarkers, argued a speaker at Internal Medicine Meeting 2026.
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Category Archives: Alzheimer Overview
Diabetes and Alzheimer’s: separating fact from fiction
You may have heard that diabetes and Alzheimer’s disease are linked. This connection can sound concerning, especially if you are living with diabetes. But understanding what the research shows can help separate facts from myths, and help you focus on what supports long‑term health. Credentialled Diabetes Educator and Registered Nurse, Carolien Koreneff, explains.
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The Next Alzheimer’s Breakthrough Will Take More Than Just Science
Alzheimer’s research is entering a new phase, as treatments that have taken decades to develop begin to reach patients. But getting those advances to people will depend on more than scientific progress alone, according to pioneering Alzheimer’s researcher John Hardy.
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Today’s Reality in Alzheimer’s Disease: Timely Detection, Collaborative Care and Real-World Impact
Key Takeaways
- Timely and accurate Alzheimer’s disease (AD) diagnosis is critical for access to care planning, including potential treatment with disease-modifying therapies.
- Strong patient-provider partnerships can enable timely assessment and treatment.
- AD blood tests are expanding access to help aid in a timely diagnosis.
- Amyloid-targeting therapies (ATTs) can help slow cognitive decline in patients with early symptomatic AD.
- Early intervention and shared decision-making empower patients and can improve real-world outcomes.
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Alzheimer’s May Begin Decades Earlier Than You Think
Alzheimer’s disease may begin its biological progression far earlier than symptoms suggest, with subtle shifts in brain and blood markers emerging decades in advance.
Scientists are uncovering a hidden phase of Alzheimer’s disease that may begin far earlier than most people realize. Long before memory loss becomes noticeable, subtle biological changes could already be underway — potentially starting in a person’s late 50s, according to new research from Mayo Clinic.
The study, published in Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association, tracks when key changes in the brain and blood begin to speed up over a person’s lifetime. The findings offer clues about the most effective timing for detection and prevention efforts.
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Restoring Dopamine Rescues Memory in Alzheimer’s Model
Why do memories fade in Alzheimer’s disease – and can they be restored?
University of California, Irvine researchers have uncovered a key mechanism underlying memory loss, showing for the first time that dopamine dysfunction in the entorhinal cortex, a critical memory-related brain region, contributes directly to impaired memory formation.
The study, published today in Nature Neuroscience, identifies a previously unrecognized role for dopamine in Alzheimer’s-related cognitive decline and points to potential therapeutic strategies using existing drugs such as Levodopa.
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