Funny play on words from the authors from Phys.org but the topic is serious enough.
A compound in beets that gives the vegetable its distinctive red color could eventually help slow the accumulation of misfolded proteins in the brain, a process that is associated with Alzheimer’s disease. Scientists say this discovery could lead to the development of drugs that could alleviate some of the long-term effects of the disease, the world’s leading cause of dementia.
The current Alzheimer’s clinical research impasse has encouraged more doctors to pursue non-pharmacological alternatives. For most individuals — beyond the up-to-5-percent who are genetically predisposed to early onset Alzheimer’s — focusing on lifestyle factors as the key to brain fitness and cognitive function, they say, is wiser than waiting for a breakthrough delivered in a pill.
A new study from The University of Texas Medical Branch at Galveston shows that using near infrared light on the heads of mice can effectively reduce vulnerability to the damaging effects of a toxic chemical in the brain known to be involved with the onset of Alzheimer’s. This data is detailed in Scientific Reports.
In March 2015, Li-Huei Tsai set up a tiny disco for some of the mice in her laboratory. For an hour each day, she placed them in a box lit only by a flickering strobe. The mice — which had been engineered to produce plaques of the peptide amyloid-β in the brain, a hallmark of Alzheimer’s disease — crawled about curiously. When Tsai later dissected them, those that had been to the mini dance parties had significantly lower levels of plaque than mice that had spent the same time in the dark1.
In a medical first, surgeons in the US implanted electrical wires into the frontal lobes of three people to stimulate their brain cells in the same way that a pacemaker regulates electrical activity in the heart.
Interesting, the video on the page in the link for today highlights life style changes while the words on the site talk about a new compound that has been found that could prevent Alzheimer’s. Both are interesting to read/watch.
“There is encouraging evidence a higher adherence to a Mediterranean diet is associated with improving cognition, slowing cognitive decline or educing the conversion to Alzheimer’s,” said Roy Hardman, from Swinburne University of Technology, Melbourne.
Eating too much salt could increase the risk of Alzheimer’s disease, according to new research.
While the US Department of Agriculture recommends we consume about three-quarters of a teaspoon of salt each day, – equivalent to about eight individual-sized bags of chips – most Americans eat nearly 50 percent more than that on a daily basis.
Experiments on mice and human cells suggest that salty foods trigger an inflammatory immune response that deprives the brain of oxygen and harms neurons, triggering behavioral and mental problems.
It has been known that people can be disoriented after general anesthesia but now a study found that propofol (a very common drug to use) also disrupts presynaptic mechanisms, probably affecting communication between neurons across the entire brain in a systematic way that differs from just being asleep. In this way it is very different than a sleeping pill
In a new study, a Salk team found that J147 binds to a protein called ATP synthase, which is responsible for producing a common cellular “energy currency” known as ATP. This protein is known to control aging in worms and flies, and the researchers found that by binding to it the drug was able to prevent age-related damage to the brain.
Research increasingly points to obesity and associated comorbidities as potential contributors to AD pathophysiology, suggesting that conditions such as prediabetes and diabetes, poor-quality diet, and a sedentary lifestyle may be modifiable risk factors.
Novel Drug Shows Promising Results in Alzheimer’s Model
Scientists report that a novel small-molecule drug, which works by stopping toxic ion flow in the brain that is known to trigger neuronal apoptosis, can restore brain function and memory in a mouse model of Alzheimer’s disease (AD). The team believes the drug could be used to treat AD and other neurodegenerative diseases such as Parkinson’s and amyotropic lateral sclerosis (ALS).
In 2013, Ms Gregory and a few others started a nonprofit group and created a website (ApoE4.info) where the community could gather. Today the group has more than 2,000 members. They pore over medical journals, reach out to top researchers in the field and share notes about their experiments with diet, exercise and other lifestyle modifications.
You would think that all would be working cooperatively towards a solution for Alzheimer’s but this is not the case. The ridiculous costs and time that it takes to run effective tests lead to a short time to recoup your research costs when you would find a workable solution. Researchers can not make a good case that this is a wise investment for Pharmaceutical companies.
So something is really wrong here and the government should look into this.
New research is suggesting that people in midlife who have a higher levels of systemic inflammation for whatever reason, later on in life, 25 years later, can show greater brain atrophy and greater problems with memory.