ibuprofen against Alzheimer’s

Alzheimer; News from the web:

The over-the-counter drug reduces inflammation in the brain, caused by a build up of rogue proteins that lead to memory loss and confusion.

If started early enough, a daily pill could reduce the chance of dementia in those most at risk.

Scientists said a simple saliva test could be used to find those people who could benefit.

They would then be put on a regular low dose of the painkiller for the rest of their lives.

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“Beeting” Alzheimer’s disease

Alzheimer; News from the web:

Funny play on words from the authors from Phys.org but the topic is serious enough.

A compound in beets that gives the vegetable its distinctive red color could eventually help slow the accumulation of misfolded proteins in the brain, a process that is associated with Alzheimer’s disease. Scientists say this discovery could lead to the development of drugs that could alleviate some of the long-term effects of the disease, the world’s leading cause of dementia.

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New research promising for prevention of cognitive decline

Alzheimer; News from the web:

A new study from The University of Texas Medical Branch at Galveston has provided researchers important insights about an enzyme within the brain that plays a critical role in Alzheimer’s.

The UTMB researchers found that blocking the enzyme helped prevent memory loss in mice.

The enzyme is a promising target for developing medications to prevent cognitive decline. The study was recently published in Alzheimer’s and Dementia: Translational Research and Clinical Interventions.

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No drugs but instead…..

Alzheimer; News from the web:

The current Alzheimer’s clinical research impasse has encouraged more doctors to pursue non-pharmacological alternatives. For most individuals — beyond the up-to-5-percent who are genetically predisposed to early onset Alzheimer’s — focusing on lifestyle factors as the key to brain fitness and cognitive function, they say, is wiser than waiting for a breakthrough delivered in a pill.

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Alzheimer’s predictions

Alzheimer; News from the web:

Heart disease deaths have actually decreased 14 percent since 2000, while Alzheimer’s deaths have increased 89 percent. Of the diseases listed in the 10 leading causes of death in the United States, Alzheimer’s is the only one that can’t be prevented, slowed or cured.

But on the positive side, there is a bloodtest in preparation that will warn you  about 20 ahead of any symptoms.

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Disco against Alzheimer’s

Alzheimer; News from the web:

In March 2015, Li-Huei Tsai set up a tiny disco for some of the mice in her laboratory. For an hour each day, she placed them in a box lit only by a flickering strobe. The mice — which had been engineered to produce plaques of the peptide amyloid-β in the brain, a hallmark of Alzheimer’s disease — crawled about curiously. When Tsai later dissected them, those that had been to the mini dance parties had significantly lower levels of plaque than mice that had spent the same time in the dark1.

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Watch out with salt!!

Alzheimer; News from the web:

Eating too much salt could increase the risk of Alzheimer’s disease, according to new research.

While the US Department of Agriculture recommends we consume about three-quarters of a teaspoon of salt each day, – equivalent to about eight individual-sized bags of chips – most Americans eat nearly 50 percent more than that on a daily basis.

Experiments on mice and human cells suggest that salty foods trigger an inflammatory immune response that deprives the brain of oxygen and harms neurons, triggering behavioral and mental problems.

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Brain muddled after surgery? Now we know why.

Alzheimer; News from the web:

It has been known that people can be disoriented after general anesthesia but now a study found that propofol (a very common drug to use) also disrupts presynaptic mechanisms, probably affecting communication between neurons across the entire brain in a systematic way that differs from just being asleep. In this way it is very different than a sleeping pill

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Another promising Alzheimer’s drug

Alzheimer; News from the web:

In a new study, a Salk team found that J147 binds to a protein called ATP synthase, which is responsible for producing a common cellular “energy currency” known as ATP. This protein is known to control aging in worms and flies, and the researchers found that by binding to it the drug was able to prevent age-related damage to the brain.

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I want to believe this

Alzheimer; News from the web:

Novel Drug Shows Promising Results in Alzheimer’s Model

  • Scientists report that a novel small-molecule drug, which works by stopping toxic ion flow in the brain that is known to trigger neuronal apoptosis, can restore brain function and memory in a mouse model of Alzheimer’s disease (AD). The team believes the drug could be used to treat AD and other neurodegenerative diseases such as Parkinson’s and amyotropic lateral sclerosis (ALS).

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What if you know you’ll have Alzheimer’s some day?

Alzheimer; News from the web:

In 2013, Ms Gregory and a few others started a nonprofit group and created a website (ApoE4.info) where the community could gather. Today the group has more than 2,000 members. They pore over medical journals, reach out to top researchers in the field and share notes about their experiments with diet, exercise and other lifestyle modifications.

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Patent law an obstacle for Alzheimer’s solutions

Alzheimer; News from the web:

You would think that all would be working cooperatively towards a solution for Alzheimer’s but this is not the case. The ridiculous costs and time that it takes to run effective tests lead to a short time to recoup your research costs when you would find a workable solution. Researchers can not make a good case that this is a wise investment for Pharmaceutical companies.

So something is really wrong here and the government should look into this.

Read all about it HERE