Scientists Uncover a Hidden Early Stage of Alzheimer’s That They Can Stop

Scientists at Tokyo Metropolitan University have turned to polymer physics to better understand one of the defining features of Alzheimer’s disease: the formation of tau protein fibrils. Their research shows that these fibrils do not form directly. Instead, tau proteins first gather into large clusters, similar to how polymers begin to crystallize. When researchers disrupted these early clusters, fibrils failed to develop in solution.

This finding points to a major shift in how future treatments for neurodegenerative diseases might be designed.

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Common Bacteria Discovered in the Eye Linked to Cognitive Decline

Chlamydia pneumoniae—a common bacterium that causes pneumonia and sinus infections—can linger in the eye and brain for years and may aggravate Alzheimer’s disease, according to a study from Cedars-Sinai. Published in Nature Communications, the discovery suggests this bacterium can amplify Alzheimer’s disease and points to potential interventions including inflammation-limiting therapies and early antibiotic treatment.

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Why people can have Alzheimer’s related brain damage but no symptoms?

Some people don’t develop dementia despite showing signs of Alzheimer’s disease in their brain, and we’re starting to understand why

Some people develop Alzheimer’s-related brain changes without experiencing symptoms of the disease, such as memory loss. We don’t know exactly why this occurs, but two recent studies are inching us closer towards an answer, with scientists revealing that these people have unusual changes in their brain that may shield them from cognitive decline.

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Cancer May Emit Signals That Protect The Brain Against Alzheimer’s

Cancer and Alzheimer’s disease are two of the most feared diagnoses in medicine, but they rarely strike the same person.

For years, epidemiologists have noticed that people with cancer seem less likely to develop Alzheimer’s, and those with Alzheimer’s are less likely to get cancer, but nobody could explain why.

new study in mice suggests a surprising possibility: certain cancers may actually send a protective signal to the brain that helps clear away the toxic protein clumps linked to Alzheimer’s disease.

Read all about it HERE