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Researchers have found that a gene called CCR2 can help with fighting memory loss for people with Alzheimer’s disease. This is a very exciting result. It may be that CCR2-associated immunity could be strengthened in humans to slow Alzheimer’s disease. The work is still in it’s early stages but the results should be encouraging.
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Last week the Food and Drug administration approved a new dye that will make it easier for doctors to spot signs of Alzheimer’s disease on brain scans.
It is a weakly radioactive dye to search for the presence of plaques in a living patient. The dye binds to the starchy amyloid that builds up in the brains of Alzheimer’s patients and can be visualized in a PET scan. It is not certain that the plaques cause Alzheimer but the presence of these plaques is highly correlated with the disease.
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Maria Carrillo, a sr director at the Alzheimer association, provides a special at CNN about Alzheimer. She tells about the 5.4 Million American who live with Alzheimer’s disease and makes it personal by talking about her own mother in law who suffers from the disease.
She then goes on to talk about the National Plan to get Alzheimer’s disease under controle by 2025. The plan covers the spectrum of Alzheimer’s issues, including treatment and prevention, clinical care, support for families in their homes and communities as well as public education and engagement.
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Researchers at the University of Rochester have identified a gene linked to Alzheimer`s disease which they say also causes a cascade of events that end with leaky blood vessels in the brain, pouring large amounts of toxic substances into brain tissue.
The scientists found that the gene, called ApoE4, works through cyclophilin A, known to be bad for the cardiovascular system, causing inflammation in atherosclerosis and other conditions.
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Researchers will test an experimental drug that could prevent Alzheimer’s disease in people who are genetically slated to develop Alzheimer’s disease but have yet to exhibit symptoms
As part of the National Alzheimer’s Plan, the National Institutes of Health (NIH) awarded a $16 million grant to Banner Alzheimer’s Institute in Arizona to fund the Alzheimer’s Prevention Initiative (API), which will study whether a plaque-fighting treatment can prevent the disease. The trial will take place in Medellín, Colombia as well as select sites in North America. The majority of the study participants will come from an extended family of 5,000 people living in Medellín who are considered part of the world’s largest family affected by Alzheimer’s. The New York Times reports the family members have a specific genetic mutation that causes symptoms of cognitive impairment around age 45, then full dementia around age 51.
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The clock is ticking: The first National Alzheimer’s Plan sets a deadline of 2025 to finally find effective ways to treat, or at least stall, the mind-destroying disease.
The Obama administration finalizes the landmark national strategy on Tuesday, laying out numerous steps the government and private partners can take over the coming years to fight what is poised to become a defining disease of the rapidly aging population.
But some of the work is beginning right away.
Starting Tuesday, embattled families and caregivers can check a new one-stop website — www.alzheimers.gov — for easy-to-understand information about dementia and where to get help in their own communities.
The National Institutes of Health is funding some major new studies of possible therapies, including a form of insulin that’s squirted into the nose.
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