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Drugs commonly found to help patients with Alzheimer now also turn out to help with osteoporosis. Patients taking donepezil and rivastigmine seemed to be less vulnerable to the risk of hip fractures.
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Here is some good news about the fight against Alzheimer. Scientist have declared a human trail successful. The new treatment involves active immunisation, using a type of vaccine designed to trigger the body’s immune defence against beta-amyloid.
In this second clinical trial on humans, the vaccine was modified to affect only the harmful beta-amyloid.
The researchers found that 80 per cent of the patients involved in the trials developed their own protective antibodies against beta-amyloid without suffering any side effects over the three years of the study.
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Researchers have found that a gene called CCR2 can help with fighting memory loss for people with Alzheimer’s disease. This is a very exciting result. It may be that CCR2-associated immunity could be strengthened in humans to slow Alzheimer’s disease. The work is still in it’s early stages but the results should be encouraging.
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Last week the Food and Drug administration approved a new dye that will make it easier for doctors to spot signs of Alzheimer’s disease on brain scans.
It is a weakly radioactive dye to search for the presence of plaques in a living patient. The dye binds to the starchy amyloid that builds up in the brains of Alzheimer’s patients and can be visualized in a PET scan. It is not certain that the plaques cause Alzheimer but the presence of these plaques is highly correlated with the disease.
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Maria Carrillo, a sr director at the Alzheimer association, provides a special at CNN about Alzheimer. She tells about the 5.4 Million American who live with Alzheimer’s disease and makes it personal by talking about her own mother in law who suffers from the disease.
She then goes on to talk about the National Plan to get Alzheimer’s disease under controle by 2025. The plan covers the spectrum of Alzheimer’s issues, including treatment and prevention, clinical care, support for families in their homes and communities as well as public education and engagement.
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Researchers at the University of Rochester have identified a gene linked to Alzheimer`s disease which they say also causes a cascade of events that end with leaky blood vessels in the brain, pouring large amounts of toxic substances into brain tissue.
The scientists found that the gene, called ApoE4, works through cyclophilin A, known to be bad for the cardiovascular system, causing inflammation in atherosclerosis and other conditions.
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