Multifunctional Drug also may help with Alzheimer’s

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University Feinberg School of Medicine have developed a new “one-size-fits-all” therapy drug that could potentially treat Alzheimer’s, Parkinson’s disease, multiple sclerosis and traumatic brain injury

The drug’s trick lies in reducing a particular type of inflammation in the brain known as neuroinflammation.  This brain response has become increasingly considered a common denominator for many neurological disorders, as well as playing a major role in brain injuries.  To decrease inflammation, the drug developed at Northwestern binds to and decreases a molecule known as cytokine, which is released in large quantities during the neuroinflammatory response.
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Major setback in Alzheimer Drug quest

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Pfizer said Monday that a highly anticipated experimental drug for Alzheimer’s disease, called bapineuzumab, wasn’t effective at slowing memory loss in a large, late-stage clinical trial in patients with a high-risk genetic mutation.

The negative result from this trial, the first of two late-stage trials on bapineuzumab to be announced this year, was expected by many scientists and investors, but it is nonetheless a disappointment to the companies and for the field of Alzheimer’s research.

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Food for Alzheimer’s

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Nestle has bought a stake in U.S. firm Accera to support the rollout of a medical food brand for Alzheimer’s patients, as the world’s biggest food group seeks to expand in the health and nutrition business
Nestle said Axona provides an alternative energy source for Alzheimer’s patients, whose brains become less able to use glucose, resulting in improved memory and cognitive function, according to ongoing clinical trials.

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Strength training to prevent Alzheimer’s

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Exercise is healthy and it is well known that staying active helps with preventing Alzheimer’s disease. New studies have however compared how well different forms of exercise were beneficial and it turns out that weight lifting or strength training is most helpful in fighting Alzheimer’s.

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Sign of Alzheimer

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Cognitive decline, eventually leading to Alzheimer’s disease, can manifest itself in many different ways. One of the early signs may be changes in the way you walk.

In the Mayo Clinic study, researchers measured the stride length, cadence and velocity of more than 1,341 participants through a computerized gait instrument at two or more visits roughly 15 months apart. Those with lower cadence, velocity and length of stride experienced significantly larger declines in global cognition, memory and executive function.

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