New research details how Alzheimer’s starts

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Past research, mainly performed on animals, suggested the aggregates form in one region then spread throughout the brain, much like how cancer spreads.

The new study suggests that while such spread may occur, it’s not in fact the main driver of disease progression.

“Once we have these seeds, little bits of aggregate throughout the brain, they just multiply and that process controls the speed,” said Meisl.

An analogy from the COVID pandemic is how travel bans between nations generally proved ineffective at stopping the spread of the virus, because it was already replicating within the countries trying to keep it out.

The team was also able to determine the time it takes the aggregates to double in number — roughly five years. That is an “encouraging” figure, said Meisl, because it shows the brain’s neurons already are good at countering aggregates. 

“Maybe if we can make it just a tiny bit better we can significantly delay the onset of serious disease.”

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Five Common Falsehoods About Alzheimer’s Disease

Alzheimer; News from the web:

The Alzheimer’s Foundation of America (AFA) is providing information to dispel common falsehoods about Alzheimer’s disease to help individuals know the warning signs, understand the importance of early detection, and learn how to be proactive about reducing their risk.

“Dispelling the misconceptions about Alzheimer’s disease is critically important, because they may cause people to ignore symptoms and delay taking action which impacts their health and quality of life,” said Charles J. Fuschillo, Jr., AFA’s President & CEO. “National Alzheimer’s Awareness Month is the perfect time to reinforce factual information that can help someone spot the warning signs, get screened, and be proactive about their brain health.”

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How about Alzheimer’s villages?

Alzheimer; News from the web:

A small village in Dax, France, is working to find a better way to handle the increasing caseload. In one of the first research projects of its kind, the small town houses around 110 people with early- to late-stage Alzheimer’s who are free to roam and visit the village’s supermarket, hairdresser, restaurant, café, library, and music hall. With a daily cost of €65 ($75), the program aims to allow people to exist with greater autonomy, purpose, and freedom without facing immediate financial hardship. “If it is not for everyone, it doesn’t work,” said Mathilde Charon-Burnel, a spokesperson for the experiment.

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Alzheimer’s and Covid; a connection found

Alzheimer; News from the web:

Researchers have identified a genetic link between Alzheimer’s and severe cases of COVID-19 that may open new avenues into the treatment of both diseases.

The study, published in the journal Brain , found that the presence of a variant of the OAS1 gene increases the risk of developing Alzheimer’s disease by three to six per cent, while similar variants of the same gene increase the odds of contracting a case of severe COVID. In addition to presenting new possibilities for treatment, researchers hope this overlap may shed light on other infectious diseases and dementias.

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