Alzheimer; News from the web:
Middle-aged men and women who opted to cycle or walk had a lower risk of developing dementia years later than their peers who rode in a car or took a bus, according to a new report.
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Alzheimer; News from the web:
Using advanced single-nuclei RNA sequencing (snRNA-seq) and a widely used preclinical model for Alzheimer’s disease, researchers from Mass General Brigham and collaborators at SUNY Upstate Medical University have identified specific brain cell types that responded most to exercise. These findings, which were validated in samples from people, shed light on the connection between exercise and brain health and point to future drug targets. Results are published in Nature Neuroscience.
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Investigators at Case Western Reserve University, University Hospitals and the Louis Stokes Cleveland VA Medical Center have identified a new and promising drug to treat AD.
The drug—and their approach by identifying a new target in the brain—showed promising results in mouse models of AD. Their findings were reported in a study published May 21 in the scientific journal Proceedings of the National Academy of Sciences (PNAS).
“Our findings suggest an effective new way to safely prevent neurodegeneration and cognitive impairment in Alzheimer’s disease by directly protecting the blood-brain barrier (BBB),” said the study’s co-lead researcher Andrew Pieper, a psychiatrist and neuroscientist, the Case Western Reserve University Rebecca E. Barchas MD DLFAPA University Professor of Translational Psychiatry and the Morley-Mather Chair of Neuropsychiatry at University Hospitals Cleveland Medical Center.
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Alzheimer; News from the web:
NIH-supported research has identified a type of immune cell that helps remove waste products in the brain. Boosting these immune cells in aged mice improved the clearance of proteins associated with Alzheimer’s disease. The findings suggest potential prevention and treatment strategies for Alzheimer’s disease and related disorders.
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Alzheimer; News from the web:
An encouraging study about the multivitamins you may already be taking, if not read the article for some good news.
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Alzheimer; News from the web:
Brain health is one of the hottest topics in the medical world, and for good reason: As more of the population ages, more people are developing dementia, a category of progressive brain disorders that includes Alzheimer’s disease. Neurosurgeon and CNN chief medical correspondent Dr. Sanjay Gupta is on a personal mission to promote brain health—as he writes in the book Keep Sharp, his grandfather died from Alzheimer’s disease—and he has isolated five science-backed ways to reduce your risk of the same fate.
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