Chlamydia pneumoniae—a common bacterium that causes pneumonia and sinus infections—can linger in the eye and brain for years and may aggravate Alzheimer’s disease, according to a study from Cedars-Sinai. Published in Nature Communications, the discovery suggests this bacterium can amplify Alzheimer’s disease and points to potential interventions including inflammation-limiting therapies and early antibiotic treatment.
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America has an Alzheimer’s problem, devastating families and driving soaring healthcare costs.
More than 7 million people over 65 years old live with Alzheimer’s dementia today, a number predicted to double by 2050. Costs are staggering, by some estimates over $1 trillion per year, which may climb to $3 trillion by 2050, or 10% of our current GDP.
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Investigators at Case Western Reserve University, University Hospitals and the Louis Stokes Cleveland VA Medical Center have identified a new and promising drug to treat AD.
The drug—and their approach by identifying a new target in the brain—showed promising results in mouse models of AD. Their findings were reported in a study published May 21 in the scientific journal Proceedings of the National Academy of Sciences (PNAS).
“Our findings suggest an effective new way to safely prevent neurodegeneration and cognitive impairment in Alzheimer’s disease by directly protecting the blood-brain barrier (BBB),” said the study’s co-lead researcher Andrew Pieper, a psychiatrist and neuroscientist, the Case Western Reserve University Rebecca E. Barchas MD DLFAPA University Professor of Translational Psychiatry and the Morley-Mather Chair of Neuropsychiatry at University Hospitals Cleveland Medical Center.
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Alzheimer; News from the web:
Read all about this study into Alzheimer’s and see if it is a good match for you or someone you know to participate.
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Alzheimer; News from the web:
The number of Americans living with Alzheimer’s continues to rise. Currently, an estimated 6.5 million Americans age 65 and older are living with Alzheimer’s — about 1 in 9. By 2050, the number is projected to reach nearly 13 million.
This and more facts and figures in the annual report from the Alzheimer’s association.
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Alzheimer; News from the web:
Read all about it HERE