Study identifies medical conditions that could predict future Alzheimer’s disease

A new study led by researchers at Vanderbilt Health has identified medical conditions that often precede an Alzheimer’s disease diagnosis. The findings, published in the journal Alzheimer’s Research & Therapy, could open opportunities to develop interventions that reduce Alzheimer’s disease risk.

Alzheimer’s disease is a neurodegenerative disorder that develops over decades. Some health conditions in midlife, such as hypertension, hyperlipidemia and stroke, have been linked to an increased risk of Alzheimer’s disease later in life, but the list of medical conditions that predict Alzheimer’s disease development is limited.

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Warning Sign That People Mistake For A Character Flaw, And It’s Actually Breaking My Heart

“The brain damage from Alzheimer’s makes people prone to agitation regardless of how loving caregivers are,” said Stefanacci, who also specializes in older populations and Alzheimer’s.

According to information the Alliance of Aging Research sent to HuffPost, “agitation” in this sense can present itself in a variety of ways: pacing, trying to leave, angry outbursts, profanity, hitting, mood swings, throwing items and more. Caregivers may blame themselves, AAR continued, thinking it’s a result of their burnout, introducing a new routine or not being patient enough. 

Study of 27.8M Americans May Have Revealed Direct Alzheimer’s Cause

Scientists have just found a direct link between air pollution and Alzheimer’s disease—suggesting that improving air quality could be an important way to prevent dementia and protect older adults. 

Alzheimer’s disease is the most common form of dementia, which affects about 57 million people worldwide, and there is currently no cure for it, making prevention is crucial. 

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AI uncovers the hidden genetic control centers driving Alzheimer’s

Scientists have created the most detailed maps yet of how genes control one another inside the brains of people with Alzheimer’s disease. Using a powerful new AI-based system called SIGNET, the team uncovered cause-and-effect relationships between genes across six major brain cell types, revealing which genes are truly driving harmful changes. The most dramatic disruptions were found in excitatory neurons, where thousands of genetic interactions appear to be extensively rewired as the disease progresses.

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The Creation Of An Alzheimer’s Detection Test

THE U.S. IS in a dementia crisis. According to a recent study published in Nature Medicine, by 2060, diagnoses of cognitive decline are expected to hit a rate of 1 million a year—double what they were in 2020. That’s one of the reasons the FDA’s approval of a new test from local drug company Eli Lilly and Swiss medication company Roche is such a big deal. Developed with help from scientists at the Indiana University School of Medicine, the test, called the Elecsys pTau181, uses blood-based biomarkers to determine the likelihood that someone with dementia symptoms has Alzheimer’s disease or if they’re suffering from another disorder.

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