Should we look at Down’s for clues about Alzheimer’s?

Alzheimer; News from the web:

At first glance, Down syndrome and Alzheimer’s disease, two severe brain abnormalities, may seem to have little in common. Down syndrome is a hereditary disease, the source of which has long been recognized — a triplication of chromosome 21. By contrast, the overwhelming majority of Alzheimer’s cases (more than 95 percent) do not have a clear-cut genetic source. Instead, the disease, which usually becomes clinically apparent late in life, is caused by a perplexing constellation of factors. While these have been the focus of intense study for more than 100 years, few conclusive answers have come to light.

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Alzheimer’s computer similation

Alzheimer; News from the web:

For the first time, scientists have developed a computer simulation of how clumps of defective proteins in neurodegenerative diseases like Alzheimer’s spread through the brain, much of the time in stealth mode, over as long as 30 years.

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Readers Digest on Alzheimer’s

Alzheimer; News from the web:

Every 65 seconds, someone develops Alzheimer’s, and their family and friends must become caregivers. Experts share the 15 things no one tells you about the challenges—and rewards.

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Overly optimistic about a cure for Alzheimer’s?

Alzheimer; News from the web:

This is the most important column I’ve ever written.  The message is quite complex–dozens of new health parameters to test for and to optimize, all of them interacting in ways that will require new training for MDs.  The message is also as simple as it can be: There is a cure for Alzheimer’s disease. You can stop reading right here, and buy two copies of Dale Bredesen’s book, one for you and one for your doctor:  The End of Alzheimer’s.

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