Alzheimer’s Disease: Music Brings Patients ‘Back to Life’

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Henry Dryer sits slumped over the tray attached to his wheelchair. He doesn’t speak, and rarely moves, until a nursing home worker puts his headphones on.

Then Dryer’s feet start to shuffle, his folded arms rock back and forth, and he sings out loud in perfect sync with his favorite songs.

“I feel a band of love, dreams,” said Dryer, 92, who has dementia. “It gives me the feeling of love, romance!”

Henry is one of seven patients profiled in the documentary “Alive Inside,” a heartwarming look at the power of music to help those in nursing homes.

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Treating Alzheimer’s Disease: A Role for the FKBP52 Protein

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New research in humans reveals that the so-called FKBP52 protein may prevent the Tau protein from turning pathogenic. This may prove significant for the development of new Alzheimer’s drugs and for detecting the disease before the onset of clinical symptoms.

A study published online March 21 in the Journal of Alzheimer’s Disease, for the first time demonstrates that the FKBP52 protein, discovered by Prof. Etienne BAULIEU twenty years ago, may prevent hyperphosphorylation of Tau protein, which has been shown to characterise a number of cerebral neurodegenerative diseases, including Alzheimer’s Disease (AD).

This work has been carried out by Professor Etienne Baulieu and his research team at Inserm (National Institute for medical research in France) with the support of philanthropists who help the Institut Baulieu, based in France.

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What If It’s Alzheimer’s?

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More than five million Americans are currently living with Alzheimer’s disease. It takes an average of 30 months from the time family members notice the first symptoms of dementia until the person is diagnosed with Alzheimer’s. There are several reasons for this, but one of the principal ones is that family members hesitate to take their loved one to a doctor, fearing that the diagnosis will in fact turn out to be Alzheimer’s.

Alzheimer’s is, above all, an insidious illness. It begins with very mild symptoms — things we all do from time to time, such as forgetting to turn off the stove, temporarily forgetting an acquaintance’s name, or misplacing the car keys. But for the person with dementia, these events will become more frequent, and with time more serious symptoms will appear.

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Alzheimer’s patients ‘should stay on drugs for longer’

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Thousands of patients with advanced Alzheimer’s disease could benefit from drugs, research suggests.

A study in the the New England Journal of Medicine found that patients who stayed on the dementia drug Aricept had a slower decline in their memory.

The drug tends not to be prescribed once sufferers progress beyond moderate symptoms.

Medicines regulator NICE said its guidelines supported continuing treatment where there were benefits.

The patent for the medicine Aricept, which is used to treat Alzheimer’s disease, expired recently. Much cheaper versions under the generic name donepezil are already available for about £12 a month.

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Coconut oil offers Alzheimer’s hope

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Oxford University researchers have discovered that coconut oil may help people with Alzheimer’s regain their memory.

Researchers say coconut oil contains unique fats known as ketones, which are thought to nourish the brain.

The results are only temporary, but researchers say the short term effects for dementia patients are astounding.

Dr Peter Clifton, a nutritional scientist, says Alzheimer’s sufferers may ‘remember who they are, who you are, and actually hold a normal conversation’.

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Tiny electrical shocks to the brain appear to enhance memory

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Lightly shocking a person’s brain just before they learned a new task appeared to strengthen memory in a handful of patients with epilepsy, a tantalizing result that could have implications for Alzheimer’s disease, U.S. researchers said on Wednesday.

Pacemaker devices known as deep brain stimulators made by Medtronic and St. Jude Medical are already used to calm muscle tremors in patients with Parkinson’s disease and other movement disorders, and are being tested for a host of other conditions such as treatment-resistant depression.

The devices are implanted under the skin in the chest with wires leading up the neck connected to tiny electrodes implanted deep in the brain, which produce electrical impulses.

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