Alzheimer; News from the web:
Research carried out by a team at University College London andrecently reported in the journal Current Biology details how molecular changes at the synapse damage memory and suggests ways that the memory loss associated with Alzheimer’s may be prevented and possibly reversed.
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Alzheimer; News from the web:
The authors demonstrate, for the first time, that a modified strain of mice generated to display human-like symptoms of Alzheimer’s show significant cognitive improvements, including a reversal of spatial memory deficit, when the brain’s expression of p62 is restored.
The study further shows that the improvement is associated with reduced levels of Aβ and associated plaques in the brain. Finally, the new research describes the mechanism by which p62 activity improves Alzheimer’s disease symptoms in mice — by a process known as autophagy. The term refers to the degradation or disassembly of unnecessary or dysfunctional components of cells — a form of biological recycling essential for cellular health.
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Alzheimer; News from the web:
Good story about different ways to communicate with an alzheimer’s patient after they have lost their capability to communicate in their regular language.
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Alzheimer; News from the web:
Known as the Prevention of Dementia by Intensive Vascular Care (pre-DIVA), the results of a cluster-randomized clinical trial showed that while the intervention did not reduce incidence of all-cause dementia, disability, or mortality, the results “do not rule out clinically meaningful effects in people with untreated hypertension who are adherent to the intervention,”
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Alzheimer; News from the web:
And thanks to a new imaging system we can see now exactly how.
Researchers at Yale University have led development in to a new type of brain scan designed to detect changes in synapses associated with common brain disorders. Until now, researchers have only be able to detect these changes during autopsies, but by combining a Positron Emission Tomography (PET) scan with a new type of injectable tracer, Yale radiology and biomedical imagining professor Richard Carson was able to measure the synaptic density in a living brain.
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Alzheimer; News from the web:
Alzheimer’s may result from the brain’s effort to fight off infections. While that hypothesis is controversial and highly speculative at this point, it could dramatically alter the way researchers and doctors work to treat and prevent the degenerative disease.
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