Stop one protein and prevent Alzheimer’s

Alzheimer; News from the web:

Alzheimer’s disease can be prevented by stopping a crucial brain protein from turning rogue, a study in mice suggests.

Lars Ittner at the University of New South Wales, Australia, and his colleagues have pinpointed a crucial enzyme that controls how tau proteins behave in the brain. The enzyme, called p38γ kinase, helps keep tau in a healthy, tangle-free state, preventing the onset of memory loss and other symptoms in mice that have been bred to develop Alzheimer’s disease.

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Finally a cure?

Alzheimer; News from the web:

By the close of this year, the Indianapolis-based Fortune 500 pharmaceutical company Lilly , whose products have included the antidepressant Prozac and human insulin, will release the results of Expedition 3, a study testing a drug that targets amyloid in persons with mild stage dementia caused by Alzheimer’s disease. Its subjects are unique. They don’t simply have Alzheimer’s disease diagnosed by a careful history and exam. They have a brain scan showing amyloid accumulation.

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