Insight in how brain atrophy can explain various manifestations of Alzheimer’s

Alzheimer; News from the web:

Mathematical modeling of the brain scans of patients with Alzheimer’s disease and others at risk for the devastating neurodegenerative disorder has identified specific patterns of brain atrophy that appear to be related to the loss of particular cognitive abilities. In their report that has been published online in the Proceedings of the National Academy of Sciences, a team of researchers at Massachusetts General Hospital (MGH) and the National University of Singapore describe how different atrophy patterns may explain the different ways that Alzheimer’s disease can be manifested in individual patients.

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Alzheimer’s may not come alone!

Alzheimer; News from the web:

The failure of many Alzheimer’s disease drug trials can be traced back to patients having a second dementia-causing ailment, Kentucky University scientists say.

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For brain screening, check my eyes.

Alzheimer; News from the web:

Diseases of the central nervous system (CNS) may manifest as pathological changes in the retina of the eye. Research from the University of Eastern Finland (UEF) shows that retinal changes may be detected earlier than brain changes. Findings from mouse models suggest that eye examination could be used as a noninvasive screening tool for human brain diseases.

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Alzheimer’s predicted by genes!

Alzheimer; News from the web:

The great majority of people will eventually develop Alzheimer’s if they don’t die of something else first.

“That’s a fundamental insight that is different in this than in other studies out there — so-called polygenic risk scores, where you look at the disease as either something you’re going to get or not,”

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