Alzheimer’s may protect you from certain cancers

Alzheimer; News from the web:

Patients with Alzheimer’s disease have a higher risk of developing glioblastoma and a lower risk of lung cancer. A paper published in Scientific Reports by researchers from the Spanish National Cancer Research Centre (CNIO), headed by Alfonso Valencia, a researcher affiliated to the CNIO and to the Barcelona Supercomputing Centre (BSC), describes the biological processes that underlie this comorbidity.

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Instead of dissolving the protein, let’s unfold it

Alzheimer; News from the web:

Researchers may have uncovered the critical missing piece that could lead to new treatments for Alzheimer’s and other neurodegenerative diseases. It’s an enzyme that plays a role in how the disease develops, but could also be harnessed to work against the tangled accumulation of proteins that eventually wreak havoc in the brains of Alzheimer’s patients.

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Heartburn meds are not a problem for Alzheimer’s after all

Alzheimer; News from the web:

Drugs used to treat acid reflux and ulcers don’t appear to boost the risk of dementia, as has been previously suspected, new research suggests.

The study focused on widely used proton pump inhibitors (PPIs) drugs — medicines such as Prevacid, Prilosec and Nexium. Previous studies have suggested the drugs may increase the risk of dementia and Alzheimer’s disease in people aged 75 and older.

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Accelerating drug discovery for Alzheimer’s

Alzheimer; News from the web:

An InSysBio scientific group led by Tatiana Karelina has developed a quantitative system pharmacology model of Alzheimer’s disease. The first part has been published in CPT Pharmacometrics & Systems Pharmacology, and shows how to design initial phases of clinical trials of new drugs and to interpret the data.

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