How language can impact Alzheimer’s trials

Alzheimer; News from the web:

According to interviews with doctors, government officials and pharmaceutical companies, few Alzheimer’s studies include medical interpreters to help patients complete the specialized neuropsychological testing component required.

One of the challenges is that clinicians and researchers have strongly cautioned against using interpreters to facilitate neuropsychological testing based on clinical experiences, observations and anecdotal evidence that they affect outcomes, according to a study published in Clinical Neuropsychology.

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Look me in the eyes

Alzheimer; News from the web:

Results from two studies show that a new, non-invasive imaging device can see signs of Alzheimer’s disease in a matter of seconds. The researchers show that the small blood vessels in the retina at the back of the eye are altered in patients with Alzheimer’s. Even patients who have a family history of Alzheimer’s but have no symptoms show these telltale signs.

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Anxiety can be a sign

Alzheimer; News from the web:

In a new study, experts found significant links between psychiatric issues like sleep disruption, anxiety, agitation, appetite changes and depression, and patterns of tan tangle burden.

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Should we look at Down’s for clues about Alzheimer’s?

Alzheimer; News from the web:

At first glance, Down syndrome and Alzheimer’s disease, two severe brain abnormalities, may seem to have little in common. Down syndrome is a hereditary disease, the source of which has long been recognized — a triplication of chromosome 21. By contrast, the overwhelming majority of Alzheimer’s cases (more than 95 percent) do not have a clear-cut genetic source. Instead, the disease, which usually becomes clinically apparent late in life, is caused by a perplexing constellation of factors. While these have been the focus of intense study for more than 100 years, few conclusive answers have come to light.

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