Trouble sleeping? It may be Alzheimer’s

Alzheimer; News from the web:

In a study with mice, the scientists at Washington University School of Medicine in St. Louis found that trouble with sleeping may be an early sign of building up of plaques in the brain that is generally correlated with Alzheimer.

Finding an early signal can be important as it will help keeping the disease under control or at least slowing it down. This in itself does not yet indicate a new way to get to a medicine of some sort.

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Alzheimer drugs

Alzheimer; News from the web:

Over at nature they have provided a great overview over the current state of affairs concerning Alzheimer drugs and research.

They also highlight the enormous costs involved in doing the clinical trails and some of the devastating results we saw this summer.

It is difficult to keep investors interested and motivated but lately there are some new paths that may just be worth exploring. Great article

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Alzheimer treatment compound found!

Alzheimer; News from the web:

Researchers from Cleveland Clinic’s Lerner Research Institute and Anesthesiology Institute found that the compound MDA7 induced beneficial immune responses that limited the development of Alzheimer’s disease.

Treatment with the compound restored cognition, memory and synaptic plasticity – a key neurological foundation of learning and memory – in an animal model.

“Cleveland Clinic dedicated two years of research into the examination of this compound and our findings show it could represent a novel therapeutic target in the treatment of Alzheimer’s disease,” Mohamed Naguib, lead researcher said in a statement.

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New biomarkers offer hope for Alzheimer

Alzheimer; News from the web:

An article has been published as supplement to the Journal of Alzheimer’s disease and it explores the development of imaging-based biomarkers that will have an impact on diagnosis before the disease process is set in motion.

Many of the detection tools we rely on today only help identify the issue once the disease symptoms are clearly visible, this research may provide a new way of detection that may in turn lead to a better understanding of the progression of the disease
.

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Possible breakthrough in Alzheimer research

Alzheimer; News from the web:

Scientist at the Harvard Medical School and researchers at the Queensland Brain Institute have found that the size of the mitochondria, the part responsible for metabolising energy in cells, matters and may cause the toxic proteins known as  Beta Amalloyd and Tau.

Apparently the larger the mitochondria the more difficult it is to travel along the nerve cells and those can be one meter in length. In tests with fruit flies and mice they have been able to test this relation between the size of the mitochondria and the incidence of Alzheimer’s disease.

The director of Queensland’s Centre for Ageing Dementia Research, Jurgen Gotz, says scientists have been able to successfully treat abnormal mitochondria in fruit flies and mice.

“By changing their size back to normal it’s possible to restore their function and also to prevent the new ones dying,” he said.

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Without a cure for Alzheimer, what can we do?

Alzheimer; News from the web:

The only protective factors against Alzheimer’s known so far appear to be increased physical activity or memory training

However frustrating it may be, there still isn’t a cure for Alzheimer’s disease and even the improved and advance scanning of the brains only serves to confirm that the disease is at a certain stage but the medicine to work at removing the stored proteins proved to be ineffective as by that time the disease is already too far down the path.

Countries with early retirement show a higher incidence of Alzheimer, pointing to a possible impact of remaining active to slow down the disease. Other research however still needs to confirm those findings and it has also been suggested that memory training does only that…..train the memory in the particular exercise used.

We continue to bring you all the research, keep coming back and spread the news so we can extend our service.

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