Scientists have just found a direct link between air pollution and Alzheimer’s disease—suggesting that improving air quality could be an important way to prevent dementia and protect older adults.
Alzheimer’s disease is the most common form of dementia, which affects about 57 million people worldwide, and there is currently no cure for it, making prevention is crucial.
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Scientists have created the most detailed maps yet of how genes control one another inside the brains of people with Alzheimer’s disease. Using a powerful new AI-based system called SIGNET, the team uncovered cause-and-effect relationships between genes across six major brain cell types, revealing which genes are truly driving harmful changes. The most dramatic disruptions were found in excitatory neurons, where thousands of genetic interactions appear to be extensively rewired as the disease progresses.
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THE U.S. IS in a dementia crisis. According to a recent study published in Nature Medicine, by 2060, diagnoses of cognitive decline are expected to hit a rate of 1 million a year—double what they were in 2020. That’s one of the reasons the FDA’s approval of a new test from local drug company Eli Lilly and Swiss medication company Roche is such a big deal. Developed with help from scientists at the Indiana University School of Medicine, the test, called the Elecsys pTau181, uses blood-based biomarkers to determine the likelihood that someone with dementia symptoms has Alzheimer’s disease or if they’re suffering from another disorder.
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Sleep duration and quality may be associated with fluid biomarkers present in Alzheimer disease, wrote authors of a systematic review published in Sleep Medicine Reviews. Specifically, short sleep duration was associated with higher levels of Alzheimer disease–related biomarkers.
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Researchers at UCLA are harnessing the power of artificial intelligence to help identify who’s at risk of Alzheimer’s disease.
Scientists are developing an AI tool to detect those cases and reduce disparities in many communities.
Alzheimer’s disease is the sixth leading cause of death in the U.S., and researchers say an early diagnosis is important for many reasons.
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Based on our past 30 years of research, we no longer think of Alzheimer’s as primarily a disease of the brain. Rather, we believe that Alzheimer’s is principally a disorder of the immune system within the brain.
The immune system, found in every organ in the body, is a collection of cells and molecules that work in harmony to help repair injuries and protect from foreign invaders.
When a person trips and falls, the immune system helps to mend the damaged tissues. When someone experiences a viral or bacterial infection, the immune system helps in the fight against these microbial invaders.
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