New Gene Thought to Be Cause in Early-Onset Forms of Alzheimer’s Disease

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A new gene that causes early-onset of Alzheimer’s disease has been discovered by the research team of Dominique Campion at the Insert unit 1079 “Genetics of cancer and neuropsychiatric diseases” in Rouen. The research scientists showed that in the families of 5 of 14 patients suffering from the disease, mutations were detected on the gene SORL1. This gene regulates the production of a peptide involved in Alzheimer’s disease.

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Vascular Dementia and Alzheimer’s Disease: Need to Study these Brain Illnesses

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Following Alzheimer’s disease, Vascular dementia is another common cause of dementia. It is hard to believe for any individual that he is suffering from such a disease which makes him forget even his own home and family. In UK, around 200,000 people are affected by this disease. But experts still have to find out the reason behind the occurrence of this illness. The origins of vascular dementia are still unknown to them.

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What If It’s Alzheimer’s?

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More than five million Americans are currently living with Alzheimer’s disease. It takes an average of 30 months from the time family members notice the first symptoms of dementia until the person is diagnosed with Alzheimer’s. There are several reasons for this, but one of the principal ones is that family members hesitate to take their loved one to a doctor, fearing that the diagnosis will in fact turn out to be Alzheimer’s.

Alzheimer’s is, above all, an insidious illness. It begins with very mild symptoms — things we all do from time to time, such as forgetting to turn off the stove, temporarily forgetting an acquaintance’s name, or misplacing the car keys. But for the person with dementia, these events will become more frequent, and with time more serious symptoms will appear.

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Is it Alzheimer’s or depression?

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Because symptoms of Alzheimer’s and depression are very similar, a wrong diagnosis can be costly.

“Chronic depression can cause a structure in your brain to shrink, and that structure is called the hippocampus and that structure is responsible for new learning and remembering,” said psychologist Dr. Shannon Gould.

While depression can be treated and often cured, Alzheimer’s can only be managed. An early diagnosis means early treatment. Neuropsychological evaluations can help determine if it’s dementia or depression.

“We are looking at attention, concentration, processing speed. I may have my patients read a short story and recall as much of that story as they can,” said Dr. Gould.

Depression is not always common in Alzheimer’s patients, but a deficit in their daily living is.

“Difficulty taking medication, maybe they are missing a dosage of medication here, or let’s say a person has always managed the finances, was impeccable with balancing the check book, now suddenly they have difficulty writing out a check properly,” said Dr. Gould.

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‘Game plan’ key for Alzheimer’s patients to manage illness

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Pat Summitt talked about her “game plan,” one of those fundamental phrases from Coaching 101 class.

Summitt was diagnosed with Alzheimer’s disease last summer and revealed it during interviews in August.

This week, Summitt will lead the Tennessee Lady Vols into the NCAA Tournament, something she has done every year since 1982. She has won eight national titles. The Lady Vols won the SEC tournament for the third- straight time.

As one of the country’s most visible Alzheimer’s victims, the awareness Summitt has brought has been invaluable.

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Alzheimer’s path found by Columbia researchers

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Columbia University researchers have made a surprising discovery about how Alzheimer’s disease appears to spread in the brain, a finding that could one day lead to early treatment for the memory-robbing disease.

The researcher’s findings – published last week in the journal PLoS One – answered a question that had stumped scientists for 25 years: does Alzheimer’s pop up independently in different parts of the brain or does it spread in a predictable pattern from one specific place in the brain to another.

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