Category Archives: Detection

Early Onset Alzheimer

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An estimated 5.4 million americans suffer from early onset Alzheimer. This represents about 10% of all who suffer from Alzheimer.

  • Severity: The symptoms of Alzheimer’s – memory loss, intellectual and behavioural disorders – take a more aggressive course in younger victims.
  • Speed: Rather than progressing over 10 to 15 years, as is the case with older patients, young-onset Alzheimer’s takes only a few years to reach an advanced stage. Mortality rates vary, but “people usually die after eight years,” says Yves Agid, a renowned neurologist and neuroscientist.

 

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Immune system helps with Alzheimer

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Researchers have found that a gene called CCR2 can help with fighting memory loss for people with Alzheimer’s disease. This is a very exciting result. It may be that CCR2-associated immunity could be strengthened in humans to slow Alzheimer’s disease. The work is still in it’s early stages but the results should be encouraging.

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New dye for brain scans

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Last week the Food and Drug administration approved a new dye that will make it easier for doctors to spot signs of Alzheimer’s disease on brain scans.

It is a weakly radioactive dye to search for the presence of plaques in a living patient. The dye binds to the starchy amyloid that builds up in the brains of Alzheimer’s patients and can be visualized in a PET scan. It is not certain that the plaques cause Alzheimer but the presence of these plaques is highly correlated with the disease.

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Clock ticking with new plan to fight Alzheimer’s

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The clock is ticking: The first National Alzheimer’s Plan sets a deadline of 2025 to finally find effective ways to treat, or at least stall, the mind-destroying disease.

The Obama administration finalizes the landmark national strategy on Tuesday, laying out numerous steps the government and private partners can take over the coming years to fight what is poised to become a defining disease of the rapidly aging population.

But some of the work is beginning right away.

Starting Tuesday, embattled families and caregivers can check a new one-stop website — www.alzheimers.gov — for easy-to-understand information about dementia and where to get help in their own communities.

The National Institutes of Health is funding some major new studies of possible therapies, including a form of insulin that’s squirted into the nose.

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FDA Approves Amyvid for Alzheimer’s Diagnosis

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Amyvid is a radiopharmaceutical developed by the Eli Lilly Company to aid in the diagnosis of Alzheimer’s disease by causing previously invisible beta amyloid plaque deposits in the brain to show up in PET scans. The FDA has recently approved Amyvid for clinical use although its use remains somewhat controversial.

Dr. Alois Alzheimer’s discovery of the physical changes in the brain in the early 1900s has caused researchers to focus on the plaque deposits he found in autopsied brains of diseased patients.  If the plaque causes the disease, discovering the plaque before a patient’s symptoms worsen could mean closing in on a cure.

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Alzheimer Diagnosis Possible With Scan

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A much-anticipated test developed by Eli Lilly LLY +0.05% & Co. that detects the presence of proteins in the brain that are related to Alzheimer’s disease was approved Friday by the Food and Drug Administration.

A much-anticipated test developed by Eli Lilly that detects the presence of proteins in the brain that are related to Alzheimer’s disease was approved Friday by the FDA . Shirley Wang has details on Lunch Break.

The tool could enable clinicians to detect Alzheimer’s earlier and more accurately in patients at the earliest sign of memory problems—a potential boon to treatment and developing drugs against the disease.

The test uses a chemical called florbetapir, known by the brand name Amyvid, which is a radioactive agent that tags clumps of a sticky substance called an amyloid. Amyloid proteins are hallmarks of Alzheimer’s disease. The chemical, which costs $1,600 per dose, then is detected using a brain imaging technique called positron emission tomography, known as PET scans.

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visit us at AlzheimerHeadlines.com