Category Archives: Detection

Clock ticking with new plan to fight Alzheimer’s

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The clock is ticking: The first National Alzheimer’s Plan sets a deadline of 2025 to finally find effective ways to treat, or at least stall, the mind-destroying disease.

The Obama administration finalizes the landmark national strategy on Tuesday, laying out numerous steps the government and private partners can take over the coming years to fight what is poised to become a defining disease of the rapidly aging population.

But some of the work is beginning right away.

Starting Tuesday, embattled families and caregivers can check a new one-stop website — www.alzheimers.gov — for easy-to-understand information about dementia and where to get help in their own communities.

The National Institutes of Health is funding some major new studies of possible therapies, including a form of insulin that’s squirted into the nose.

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FDA Approves Amyvid for Alzheimer’s Diagnosis

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Amyvid is a radiopharmaceutical developed by the Eli Lilly Company to aid in the diagnosis of Alzheimer’s disease by causing previously invisible beta amyloid plaque deposits in the brain to show up in PET scans. The FDA has recently approved Amyvid for clinical use although its use remains somewhat controversial.

Dr. Alois Alzheimer’s discovery of the physical changes in the brain in the early 1900s has caused researchers to focus on the plaque deposits he found in autopsied brains of diseased patients.  If the plaque causes the disease, discovering the plaque before a patient’s symptoms worsen could mean closing in on a cure.

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Alzheimer Diagnosis Possible With Scan

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A much-anticipated test developed by Eli Lilly LLY +0.05% & Co. that detects the presence of proteins in the brain that are related to Alzheimer’s disease was approved Friday by the Food and Drug Administration.

A much-anticipated test developed by Eli Lilly that detects the presence of proteins in the brain that are related to Alzheimer’s disease was approved Friday by the FDA . Shirley Wang has details on Lunch Break.

The tool could enable clinicians to detect Alzheimer’s earlier and more accurately in patients at the earliest sign of memory problems—a potential boon to treatment and developing drugs against the disease.

The test uses a chemical called florbetapir, known by the brand name Amyvid, which is a radioactive agent that tags clumps of a sticky substance called an amyloid. Amyloid proteins are hallmarks of Alzheimer’s disease. The chemical, which costs $1,600 per dose, then is detected using a brain imaging technique called positron emission tomography, known as PET scans.

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New Gene Thought to Be Cause in Early-Onset Forms of Alzheimer’s Disease

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A new gene that causes early-onset of Alzheimer’s disease has been discovered by the research team of Dominique Campion at the Insert unit 1079 “Genetics of cancer and neuropsychiatric diseases” in Rouen. The research scientists showed that in the families of 5 of 14 patients suffering from the disease, mutations were detected on the gene SORL1. This gene regulates the production of a peptide involved in Alzheimer’s disease.

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Vascular Dementia and Alzheimer’s Disease: Need to Study these Brain Illnesses

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Following Alzheimer’s disease, Vascular dementia is another common cause of dementia. It is hard to believe for any individual that he is suffering from such a disease which makes him forget even his own home and family. In UK, around 200,000 people are affected by this disease. But experts still have to find out the reason behind the occurrence of this illness. The origins of vascular dementia are still unknown to them.

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What If It’s Alzheimer’s?

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More than five million Americans are currently living with Alzheimer’s disease. It takes an average of 30 months from the time family members notice the first symptoms of dementia until the person is diagnosed with Alzheimer’s. There are several reasons for this, but one of the principal ones is that family members hesitate to take their loved one to a doctor, fearing that the diagnosis will in fact turn out to be Alzheimer’s.

Alzheimer’s is, above all, an insidious illness. It begins with very mild symptoms — things we all do from time to time, such as forgetting to turn off the stove, temporarily forgetting an acquaintance’s name, or misplacing the car keys. But for the person with dementia, these events will become more frequent, and with time more serious symptoms will appear.

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