Category Archives: Detection

Alzheimer’s changes start 25 years early

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The first Alzheimer’s-related changes begin to develop some 25 years before memory and thinking problems appear, according to a new study that may offer a valuable guide for companies looking to test new treatments in people at an earlier stage.

The study, published on Wednesday in the New England Journal of Medicine, offers a timeline of changes in spinal fluid, brain size, the appearance of brain plaques and other factors that precede the onset of Alzheimer’s in people who are genetically predestined to develop the brain-wasting disease.

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Early Onset Alzheimer

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An estimated 5.4 million americans suffer from early onset Alzheimer. This represents about 10% of all who suffer from Alzheimer.

  • Severity: The symptoms of Alzheimer’s – memory loss, intellectual and behavioural disorders – take a more aggressive course in younger victims.
  • Speed: Rather than progressing over 10 to 15 years, as is the case with older patients, young-onset Alzheimer’s takes only a few years to reach an advanced stage. Mortality rates vary, but “people usually die after eight years,” says Yves Agid, a renowned neurologist and neuroscientist.

 

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Immune system helps with Alzheimer

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Researchers have found that a gene called CCR2 can help with fighting memory loss for people with Alzheimer’s disease. This is a very exciting result. It may be that CCR2-associated immunity could be strengthened in humans to slow Alzheimer’s disease. The work is still in it’s early stages but the results should be encouraging.

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New dye for brain scans

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Last week the Food and Drug administration approved a new dye that will make it easier for doctors to spot signs of Alzheimer’s disease on brain scans.

It is a weakly radioactive dye to search for the presence of plaques in a living patient. The dye binds to the starchy amyloid that builds up in the brains of Alzheimer’s patients and can be visualized in a PET scan. It is not certain that the plaques cause Alzheimer but the presence of these plaques is highly correlated with the disease.

Read all about it HERE

visit us at AlzheimerHeadlines.com