Glial-to-neuron conversion therapy decreases inflammation and restores the brain-blood barrier in Alzheimer’s disease model macaques.

In search of an innovative medicine, a group of scientists at Jinan University in Guangdong, China, has developed a disease-modifying therapy that, when tested in a non-human primate Alzheimer’s model, has shown improvements in both biological markers and clinical aspects of the disease. “These outcomes offer new hope for the tens of millions of Alzheimer’s patients worldwide,” says Wenliang Lei, principal investigator at Guangdong-Hong Kong-Macau Institute of CNS Regeneration (GHMICR) in Jinan University, and co-corresponding author of the study published in Advanced Science.

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